Abstract

The functions of this Core Facility are to employ flow cytometric analysis and fluorescence activated cell sorting to solve problems in cancer research. The Core Facility provides comprehensive support of this technology in order to facilitate utilization by a variety of investigators. Specifically, the Core facility: A. maintains a state-of-the-art dual laser flow cytometer/cell sorter which is the only flow cytometer with cell sorting capability at Georgetown UniVersity; B. provides a trained operator to insure efficient and correct use of this complex instrumentation; C. provides personnel to assist with the development and application of a variety of fluorescence labeling methods; D. provides expertise for the innovative application of this instrumentation in order to fully exploit the capabilities of this technology for cancer research. Sixty-one investigators (57 LCRC members) from 13 different departments at Georgetown have used this Core Facility since the instrument was installed in 1989; 25 LCRC investigators with peer reviewed funding utilized this facility during the past year (July 1, 1991 to June 30, 1992).

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA051008-06
Application #
3731004
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
6
Fiscal Year
1995
Total Cost
Indirect Cost

  Institution

Name
Georgetown University
Department
Type
DUNS #
049515844
City
Washington
State
DC
Country
United States
Zip Code
20057

  Publications

Alamri, Ahmad M; Liu, Xuefeng; Blancato, Jan K et al. (2018) Expanding primary cells from mucoepidermoid and other salivary gland neoplasms for genetic and chemosensitivity testing. Dis Model Mech 11:
Naab, Tammey J; Gautam, Anita; Ricks-Santi, Luisel et al. (2018) MYC amplification in subtypes of breast cancers in African American women. BMC Cancer 18:274
Hinzman, Charles P; Baulch, Janet E; Mehta, Khyati Y et al. (2018) Exposure to Ionizing Radiation Causes Endoplasmic Reticulum Stress in the Mouse Hippocampus. Radiat Res 190:483-493
Nomura, Sarah J O; Hwang, Yi-Ting; Gomez, Scarlett Lin et al. (2018) Dietary intake of soy and cruciferous vegetables and treatment-related symptoms in Chinese-American and non-Hispanic White breast cancer survivors. Breast Cancer Res Treat 168:467-479
Burks, Julian; Nadella, Sandeep; Mahmud, Abdullah et al. (2018) Cholecystokinin Receptor-Targeted Polyplex Nanoparticle Inhibits Growth and Metastasis of Pancreatic Cancer. Cell Mol Gastroenterol Hepatol 6:17-32
Lelo, Alana; Prip, Frederik; Harris, Brent T et al. (2018) STAG2 Is a Biomarker for Prediction of Recurrence and Progression in Papillary Non-Muscle-Invasive Bladder Cancer. Clin Cancer Res 24:4145-4153
Tassi, Elena; Lai, En Yin; Li, Lingli et al. (2018) Blood Pressure Control by a Secreted FGFBP1 (Fibroblast Growth Factor-Binding Protein). Hypertension 71:160-167
Sponholtz, Todd R; Palmer, Julie R; Rosenberg, Lynn A et al. (2018) Exogenous Hormone Use and Endometrial Cancer in U.S. Black Women. Cancer Epidemiol Biomarkers Prev 27:558-565
Kumar, Santosh; Suman, Shubhankar; Fornace Jr, Albert J et al. (2018) Space radiation triggers persistent stress response, increases senescent signaling, and decreases cell migration in mouse intestine. Proc Natl Acad Sci U S A 115:E9832-E9841
Choudhary, Saba; Ramasundaram, Poornema; Dziopa, Eugenia et al. (2018) Human ex vivo 3D bone model recapitulates osteocyte response to metastatic prostate cancer. Sci Rep 8:17975

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