Abstract

The core facility for the synthesis and sequence analysis of macromolecules provides Lombardi Cancer Center investigators with the facilities for protein sequencing, peptide synthesis, DNA synthesis, DNA sequencing, and densitometry. In 1991, the core facility was utilized by 38 Georgetown University investigators from 11 different departments. Of these users, more than 95% were members of the Lombardi Cancer Center. 84% of the projects utilizing the core facility over the past year were supported by peer-reviewed funding. The core facility is utilized by all of the program areas in this proposal. The core facility is supported by CCSG funding, user fees, and other institutional funding.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA051008-07
Application #
5207616
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
7
Fiscal Year
1996
Total Cost
Indirect Cost

  Publications

Lee, Shiao-Pieng; Kao, Chen-Yu; Chang, Shun-Cheng et al. (2018) Tissue distribution and subcellular localizations determine in vivo functional relationship among prostasin, matriptase, HAI-1, and HAI-2 in human skin. PLoS One 13:e0192632
Paffhausen, Emily S; Alowais, Yasir; Chao, Cara W et al. (2018) Discovery of a stem-like multipotent cell fate. Am J Stem Cells 7:25-37
Akinyemiju, Tomi F; Demb, Joshua; Izano, Monika A et al. (2018) The association of early life socioeconomic position on breast cancer incidence and mortality: a systematic review. Int J Public Health 63:787-797
Tiek, D M; Rone, J D; Graham, G T et al. (2018) Alterations in Cell Motility, Proliferation, and Metabolism in Novel Models of Acquired Temozolomide Resistant Glioblastoma. Sci Rep 8:7222
Furth, Priscilla A (2018) Peroxisome proliferator-activated receptor gamma and BRCA1. Endocr Relat Cancer :
Sehrawat, Archana; Gao, Lina; Wang, Yuliang et al. (2018) LSD1 activates a lethal prostate cancer gene network independently of its demethylase function. Proc Natl Acad Sci U S A 115:E4179-E4188
Gusev, Yuriy; Bhuvaneshwar, Krithika; Song, Lei et al. (2018) The REMBRANDT study, a large collection of genomic data from brain cancer patients. Sci Data 5:180158
Oppong, Bridget A; Dash, Chiranjeev; O'Neill, Suzanne et al. (2018) Breast density in multiethnic women presenting for screening mammography. Breast J 24:334-338
Fernandez, Harvey R; Gadre, Shreyas M; Tan, Mingjun et al. (2018) The mitochondrial citrate carrier, SLC25A1, drives stemness and therapy resistance in non-small cell lung cancer. Cell Death Differ 25:1239-1258
Schmidt, Marcel Oliver; Garman, Khalid Ammar; Lee, Yong Gu et al. (2018) The Role of Fibroblast Growth Factor-Binding Protein 1 in Skin Carcinogenesis and Inflammation. J Invest Dermatol 138:179-188

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