Abstract

The Informatics Shared Resource (ISR) of the Cancer Research Center of Hawafi (CRCH) was established as a core facility in 2004. Its goal is to promote multidisciplinary collaboration, and enhance the research excellence and productivity of CRCH by providing access to informatics expertise and computational support to all members of the Center. The prime objective of the ISR is to facilitate the management, sharing, and integration of data, as well as synthesis of data sets from basic, clinical, and population sciences. In addition to the support in broad-spectrum informatics and computing infrastructure, the bioinformatics group of the ISR also collaborates with investigators to help incorporate cutting-edge genomic and/or proteomic approaches in their research. Services of the ISR include consultation on informatics issues; computer software review and algorithm development; database system design, maintenance, and programming; guidance for storage, extraction, sharing and integration of data from diverse sources as well as support for analytic tools that enable investigators to take full advantage of advanced computational methods to expand their research capacity.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA071789-09
Application #
7110858
Study Section
Subcommittee G - Education (NCI)
Project Start
2005-07-01
Project End
2009-06-30
Budget Start
2005-07-01
Budget End
2006-06-30
Support Year
9
Fiscal Year
2005
Total Cost
$52,138
Indirect Cost

  Institution

Name
University of Hawaii
Department
Type
DUNS #
965088057
City
Honolulu
State
HI
Country
United States
Zip Code
96822

  Publications

Marciel, Michael P; Rose, Aaron H; Martinez, Verena et al. (2018) Calpain-2 inhibitor treatment preferentially reduces tumor progression for human colon cancer cells expressing highest levels of this enzyme. Cancer Med 7:175-183
Shi, Geng-Xian; Yang, Won Seok; Jin, Ling et al. (2018) RSK2 drives cell motility by serine phosphorylation of LARG and activation of Rho GTPases. Proc Natl Acad Sci U S A 115:E190-E199
Citronberg, Jessica S; Wilkens, Lynne R; Le Marchand, Loic et al. (2018) Plasma lipopolysaccharide-binding protein and colorectal cancer risk: a nested case-control study in the Multiethnic Cohort. Cancer Causes Control 29:115-123
Panizza, Chloe E; Shvetsov, Yurii B; Harmon, Brook E et al. (2018) Testing the Predictive Validity of the Healthy Eating Index-2015 in the Multiethnic Cohort: Is the Score Associated with a Reduced Risk of All-Cause and Cause-Specific Mortality? Nutrients 10:
Marciel, Michael P; Khadka, Vedbar S; Deng, Youpeng et al. (2018) Selenoprotein K deficiency inhibits melanoma by reducing calcium flux required for tumor growth and metastasis. Oncotarget 9:13407-13422
Park, S-Y; Wilkens, L R; Maskarinec, G et al. (2018) Weight change in older adults and mortality: the Multiethnic Cohort Study. Int J Obes (Lond) 42:205-212
Gong, J; Nishimura, K K; Fernandez-Rhodes, L et al. (2018) Trans-ethnic analysis of metabochip data identifies two new loci associated with BMI. Int J Obes (Lond) 42:384-390
Pokhrel, Pallav; Herzog, Thaddeus A; Fagan, Pebbles et al. (2018) E-cigarette Advertising Exposure, Explicit and Implicit Harm Perceptions, and E-Cigarette use Susceptibility Among Non-Smoking Young Adults. Nicotine Tob Res :
Wu, Eric M; Hernandez, Brenda Y; Wong, Linda L (2018) Hepatocellular carcinoma in Micronesians, a growing Pacific Islander population in the U.S. Open J Gastroenterol 8:
Murphy, Sharon E; von Weymarn, Linda B; Parenteau, Marc et al. (2018) Influence of UGT2B10 Genotype on Urinary Excretion of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol- N-glucuronide by African American Smokers. Chem Res Toxicol 31:168-175

Showing the most recent 10 out of 562 publications