The Nutrition Support Shared Resource (NSSR) provides dietary assessment information to support diet- related cancer research studies. NSSR plays a role in the discovery process for mechanisms and pathways of diet?s direct impact on cancer. Unique to the activities of this Hawai?i based shared resource is the exploration and quantification of diets influenced by the diverse backgrounds of the citizens of Hawai?i and the Pacific. NSSR provides UHCC members consultation in the design and execution of studies addressing dietary intakes or nutritional status. NSSR also maintains current food and supplement composition databases, coordinates nutrition related studies following best practices, and provides education and training in food and nutrition methods relevant to cancer research. The structure of the databases allows for frequent updates, as well as additions of nutrients and food components as new hypotheses are developed by UHCC investigators. Numerous dietary questionnaires, appropriate for studies of specific cancers, have been developed and are widely used by investigators within the Cancer Center, as well as in collaborating institutions. The quality of the science is assured by having a central resource providing all dietary assessment services. In addition, projects can be undertaken systematically as dictated by advances in scientific knowledge and by investigator needs. Results of dietary studies within UHCC can be pooled without worry of different food composition databases having been used as may occur if a central resource were not available. Specialization also ensures projects are completed in a timely manner. As a result of having a central resource, the research conducted by the Cancer Center investigators can incorporate dietary assessment and analysis methodology that reflects the current evidence base in these areas. The NSSR staff have extensive experience in all aspects of nutritional assessment including dietary intake, anthropometry, and nutritional status which aids the design, data collection and entry, data analysis, and interpretation skills required to complete studies addressing cancer research. Recommendations of best methods based on proposed study design and desired outcomes are essential for meaningful results. The CCSG provides stability for these activities and ensures that the NSSR remains in the forefront of dietary assessment methodology when providing assistance to UHCC members.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA071789-18
Application #
9572512
Study Section
Subcommittee I - Transistion to Independence (NCI)
Project Start
Project End
Budget Start
2018-07-01
Budget End
2019-06-30
Support Year
18
Fiscal Year
2018
Total Cost
Indirect Cost
Name
University of Hawaii
Department
Type
DUNS #
965088057
City
Honolulu
State
HI
Country
United States
Zip Code
96822
Marciel, Michael P; Khadka, Vedbar S; Deng, Youpeng et al. (2018) Selenoprotein K deficiency inhibits melanoma by reducing calcium flux required for tumor growth and metastasis. Oncotarget 9:13407-13422
Park, S-Y; Wilkens, L R; Maskarinec, G et al. (2018) Weight change in older adults and mortality: the Multiethnic Cohort Study. Int J Obes (Lond) 42:205-212
Gong, J; Nishimura, K K; Fernandez-Rhodes, L et al. (2018) Trans-ethnic analysis of metabochip data identifies two new loci associated with BMI. Int J Obes (Lond) 42:384-390
Pokhrel, Pallav; Herzog, Thaddeus A; Fagan, Pebbles et al. (2018) E-cigarette Advertising Exposure, Explicit and Implicit Harm Perceptions, and E-Cigarette use Susceptibility Among Non-Smoking Young Adults. Nicotine Tob Res :
Wu, Eric M; Hernandez, Brenda Y; Wong, Linda L (2018) Hepatocellular carcinoma in Micronesians, a growing Pacific Islander population in the U.S. Open J Gastroenterol 8:
Murphy, Sharon E; von Weymarn, Linda B; Parenteau, Marc et al. (2018) Influence of UGT2B10 Genotype on Urinary Excretion of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol- N-glucuronide by African American Smokers. Chem Res Toxicol 31:168-175
Loo, Lenora W M; Williams, Makana; Hernandez, Brenda Y (2018) The high and heterogeneous burden of breast cancer in Hawaii: A unique multiethnic U.S. Population. Cancer Epidemiol 58:71-76
Hernandez, Brenda Y; Tareg, Aileen C; Reichhardt, Martina et al. (2018) Randomized controlled trial evaluating the utility of urine HPV DNA for cervical cancer screening in a Pacific Island population. J Glob Health Rep 2:
Gu, Yuanzhuo; Wei, Xiyang; Sun, Yulin et al. (2018) miR-192-5p silencing by genetic aberrations is a key event in hepatocellular carcinomas with cancer stem cell features. Cancer Res :
Lim, Unhee; Monroe, Kristine R; Buchthal, Steve et al. (2018) Propensity for Intra-abdominal and Hepatic Adiposity Varies Among Ethnic Groups. Gastroenterology :

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