Protocol Review & Monitoring SystemThe Protocol Review & Monitoring System (PRMS) at Moffitt Cancer Center facilitates the function of twoScientific Review Committees (SRCs), each staffed with appropriate faculty and scientific representation.Each committee meets once a month, with staggered meetings so that there is an SRC meetingapproximately every two weeks. The SRCs provide the review for scientific merit and prioritization andmonitor scientific progress for all protocols at the Cancer Center. SRC approval is required prior to IRBsubmission and the IRB will not consider a research study from the Cancer Center that has not beenapproved by the Moffitt Cancer Center SRC. The SRCs have reviewed between 180 and 200 new protocolseach year of the grant for scientific merit. Protocols that have been previously peer reviewed by recognizedpeer-review agencies are expedited through the SRC process, but are reviewed administratively by the Chairor his designee.The committees review all ongoing clinical research studies for scientific progress and have the authority tosuspend and close studies that are not making scientific progress towards their objectives.The Cancer Center is in the process of implementing the Oncore clinical trials management software thatwill aid the PRMS in the administrative tracking of all research studies (pending and ongoing), as well asfacilitate the committee process by helping to coordinate the committee membership, agendas, decisionsand correspondence.

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National Cancer Institute (NCI)
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Subcommittee G - Education (NCI)
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H. Lee Moffitt Cancer Center & Research Institute
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