Protocol Review & Monitoring SystemThe Protocol Review & Monitoring System (PRMS) at Moffitt Cancer Center facilitates the function of twoScientific Review Committees (SRCs), each staffed with appropriate faculty and scientific representation.Each committee meets once a month, with staggered meetings so that there is an SRC meetingapproximately every two weeks. The SRCs provide the review for scientific merit and prioritization andmonitor scientific progress for all protocols at the Cancer Center. SRC approval is required prior to IRBsubmission and the IRB will not consider a research study from the Cancer Center that has not beenapproved by the Moffitt Cancer Center SRC. The SRCs have reviewed between 180 and 200 new protocolseach year of the grant for scientific merit. Protocols that have been previously peer reviewed by recognizedpeer-review agencies are expedited through the SRC process, but are reviewed administratively by the Chairor his designee.The committees review all ongoing clinical research studies for scientific progress and have the authority tosuspend and close studies that are not making scientific progress towards their objectives.The Cancer Center is in the process of implementing the Oncore clinical trials management software thatwill aid the PRMS in the administrative tracking of all research studies (pending and ongoing), as well asfacilitate the committee process by helping to coordinate the committee membership, agendas, decisionsand correspondence.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA076292-09
Application #
7516343
Study Section
Subcommittee G - Education (NCI)
Project Start
2007-02-01
Project End
2012-01-31
Budget Start
2007-02-01
Budget End
2008-01-31
Support Year
9
Fiscal Year
2007
Total Cost
$132,869
Indirect Cost
Name
H. Lee Moffitt Cancer Center & Research Institute
Department
Type
DUNS #
139301956
City
Tampa
State
FL
Country
United States
Zip Code
33612
Divakaran, Anand; Talluri, Siva K; Ayoub, Alex M et al. (2018) Molecular Basis for the N-Terminal Bromodomain-and-Extra-Terminal-Family Selectivity of a Dual Kinase-Bromodomain Inhibitor. J Med Chem 61:9316-9334
de Mingo Pulido, Álvaro; Gardner, Alycia; Hiebler, Shandi et al. (2018) TIM-3 Regulates CD103+ Dendritic Cell Function and Response to Chemotherapy in Breast Cancer. Cancer Cell 33:60-74.e6
Li, Gongbo; Boucher, Justin C; Kotani, Hiroshi et al. (2018) 4-1BB enhancement of CAR T function requires NF-?B and TRAFs. JCI Insight 3:
McIntyre, Jessica; Jiménez, Julio; Rivera, Yonaira M et al. (2018) Comparison of Health Communication Channels for Reaching Hispanics About Biobanking: a Pilot Trial. J Cancer Educ 33:833-841
Saltos, Andreas; Khalil, Farah; Smith, Michelle et al. (2018) Clinical associations of mucin 1 in human lung cancer and precancerous lesions. Oncotarget 9:35666-35675
Rivera, Y M; Moreno, L; Briant, K J et al. (2018) Developing Sustainable Cancer Education Programs: Training Public Health Students to Deliver Cancer 101 in Puerto Rico. J Cancer Educ 33:128-133
Maharaj, Kamira; Powers, John J; Achille, Alex et al. (2018) Silencing of HDAC6 as a therapeutic target in chronic lymphocytic leukemia. Blood Adv 2:3012-3024
Gjyshi, Anxhela; Dash, Sweta; Cen, Ling et al. (2018) Early transcriptional response of human ovarian and fallopian tube surface epithelial cells to norepinephrine. Sci Rep 8:8291
Zhu, Genyuan; Brayer, Jason; Padron, Eric et al. (2018) OMIP-049: Analysis of Human Myelopoiesis and Myeloid Neoplasms. Cytometry A 93:982-986
Schaal, Courtney M; Bora-Singhal, Namrata; Kumar, Durairaj Mohan et al. (2018) Regulation of Sox2 and stemness by nicotine and electronic-cigarettes in non-small cell lung cancer. Mol Cancer 17:149

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