The Developmental Research Core will provide a framework for interpreting and responding to new research initiatives by allocating resources to programs that support meritorious scientific investigations and expand the current biomedical research enterprise to the greatest extend possible. Core funds will be allocated using a well-defined, incrementally implemented peer-reviewed research program managed by the Administrative Core with direct supervisory input from the Steering Committee and the Scientific Advisory Board. The purpose will be to stimulated and catalyze innovative multidisciplinary pilot projects among the scientists of the center, specifically between AIDS researchers and Basic and clinical scientists in other departments and schools (Category I awards); provide protected time for meritorious young investigators to pursue independent competitive research programs (Category II awards); and aid departments of the four involved institutions in the recruitment of new investigators with investigative interests that compliment the activities of center members (Category III Awards). Outcomes will be measured to improve quality and effectiveness. Accountability for expenditures will be required.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
3P30CA079458-04S1
Application #
6666297
Study Section
Project Start
2002-09-26
Project End
2003-08-31
Budget Start
Budget End
Support Year
4
Fiscal Year
2002
Total Cost
Indirect Cost
Name
Northwestern University at Chicago
Department
Type
DUNS #
005436803
City
Chicago
State
IL
Country
United States
Zip Code
60611
Estes, Jacob D; Haase, Ashley T; Schacker, Timothy W (2008) The role of collagen deposition in depleting CD4+ T cells and limiting reconstitution in HIV-1 and SIV infections through damage to the secondary lymphoid organ niche. Semin Immunol 20:181-6
Estes, Jacob; Baker, Jason V; Brenchley, Jason M et al. (2008) Collagen deposition limits immune reconstitution in the gut. J Infect Dis 198:456-64
Reilly, Cavan; Raghavan, Arvind; Bohjanen, Paul (2006) Global assessment of cross-hybridization for oligonucleotide arrays. J Biomol Tech 17:163-72
Schacker, Timothy W; Brenchley, Jason M; Beilman, Gregory J et al. (2006) Lymphatic tissue fibrosis is associated with reduced numbers of naive CD4+ T cells in human immunodeficiency virus type 1 infection. Clin Vaccine Immunol 13:556-60
Reilly, Cavan (2005) A nonparametric approach to the analysis of longitudinal data via a set of level crossing problems with application to the analysis of microarray time course experiments. Biostatistics 6:271-8
Schleyer, Titus K L; Teasley, Stephanie D; Bhatnagar, Rishi (2005) Comparative case study of two biomedical research collaboratories. J Med Internet Res 7:e53
Li, Qingsheng; Schacker, Timothy; Carlis, John et al. (2004) Functional genomic analysis of the response of HIV-1-infected lymphatic tissue to antiretroviral therapy. J Infect Dis 189:572-82
Krathwohl, Mitchell D; Kaiser, Jodi L (2004) HIV-1 promotes quiescence in human neural progenitor cells. J Infect Dis 190:216-26
Ruth, Jeffrey H; Shahrara, Shiva; Park, Christy C et al. (2003) Role of macrophage inflammatory protein-3alpha and its ligand CCR6 in rheumatoid arthritis. Lab Invest 83:579-88
Pope, Melissa; Haase, Ashley T (2003) Transmission, acute HIV-1 infection and the quest for strategies to prevent infection. Nat Med 9:847-52

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