The Tissue Procurement Core of the HCCC is designed to procure and make available a wide range of high quality human tissue specimens to investigators from the HCCC while complying with all governing rules and regulations covering such activty. The core was initiated approximately 24 months ago as a collaboration between the HCCC and the Department of Pathology at the University of Iowa Hospitals and Clinics. The Core Director also serves as Director of Anatomic and Surgical Pathology for the Ul Hospitals and Clinics which facilitates this process. Tissue procurement began slowly as processes were developed. To date, the core has collected in excess of 1,000 specimens. At the present time, the core now averages approximately 90 specimens per month. Importantly, both procurement and tissue distribution by the Core are now fully operational. The Tissue Procurement Core is dedicated to the collection, storage, and distribution of high quality human tissue specimens from a variety of disease processes. The process of specimen collection proceeds in a deliberate and step wise fashion. Pre-operative patient consent is mandatory and is obtained either by Tissue Procurement Service Staff or by HCCC/UIHC medical staff at pre-operative visits. Once consent has been obtained, the patient proceeds to surgery to have their appropriate procedure performed. Tissue removed at surgery is then evaluated in the Surgical Pathology Laboratory for suitability of collection by appropriate Department of Pathology staff. Tissue Procurement Core personnel, working in cooperation with Surgical Pathology Laboratory Personnel, take appropriate specimens for archiving. The specimens are snap frozen

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA086862-10
Application #
7900767
Study Section
Subcommittee G - Education (NCI)
Project Start
2009-07-01
Project End
2010-06-30
Budget Start
2009-07-01
Budget End
2010-06-30
Support Year
10
Fiscal Year
2009
Total Cost
$104,308
Indirect Cost
Name
University of Iowa
Department
Type
DUNS #
062761671
City
Iowa City
State
IA
Country
United States
Zip Code
52242
Chiba, Akiko; Raman, Rachna; Thomas, Alexandra et al. (2018) Serum Vitamin D Levels Affect Pathologic Complete Response in Patients Undergoing Neoadjuvant Systemic Therapy for Operable Breast Cancer. Clin Breast Cancer 18:144-149
Vikas, Praveen; Borcherding, Nicholas; Zhang, Weizhou (2018) The clinical promise of immunotherapy in triple-negative breast cancer. Cancer Manag Res 10:6823-6833
Alexander, Matthew S; Cullen, Joseph J (2018) Treating pancreatic cancer: more antioxidants more problems? Expert Rev Gastroenterol Hepatol 12:849-851
Lin, Jie; Adjeroh, Donald A; Jiang, Bing-Hua et al. (2018) K2 and K2*: efficient alignment-free sequence similarity measurement based on Kendall statistics. Bioinformatics 34:1682-1689
Koppenhafer, Stacia L; Goss, Kelli L; Terry, William W et al. (2018) mTORC1/2 and Protein Translation Regulate Levels of CHK1 and the Sensitivity to CHK1 Inhibitors in Ewing Sarcoma Cells. Mol Cancer Ther 17:2676-2688
Lutgendorf, Susan K; Thaker, Premal H; Arevalo, Jesusa M et al. (2018) Biobehavioral modulation of the exosome transcriptome in ovarian carcinoma. Cancer 124:580-586
Krishnamani, Venkatramanan; Peterson, Tabitha A; Piper, Robert C et al. (2018) Informatic Analysis of Sequence Data from Batch Yeast 2-Hybrid Screens. J Vis Exp :
Al-Qurayshi, Zaid; Khadra, Helmi; Chang, Kristi et al. (2018) Risk and survival of patients with medullary thyroid cancer: National perspective. Oral Oncol 83:59-63
Wang, Sophia S; Carrington, Mary; Berndt, Sonja I et al. (2018) HLA Class I and II Diversity Contributes to the Etiologic Heterogeneity of Non-Hodgkin Lymphoma Subtypes. Cancer Res 78:4086-4096
Campbell, Hannah; Heidema, Christy; Pilarczyk, Daisy G et al. (2018) SHP-2 is activated in response to force on E-cadherin and dephosphorylates vinculin Y822. J Cell Sci 131:

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