Tissue Procurement Core Ready access to both benign and malignant tissue is a valuable resource for cancer investigators. The Tissue Procurement Core is designed to collect and store high quality tissue specimens from a variety of sources and make these available to HCCC investigators based on the science proposed. The Core insures that these activities are performed in compliance with all rules and regulations covering such activity. The Core and its personnel work in cooperation with clinicians from various departments to: 1) Identify and consent patients from whom collection may be appropriate. 2) Work closely with appropriate individuals in the Surgical Pathology Laboratory to insure adequate patient care while maximizing the number of collected specimens 3) Enter information about specimens into a secure data base and store appropriately 4) Implement rigorous quality control procedures 5) Distribute available tissue to investigators for high quality cancer research The HCCC and University of lowa CTSA are collaborating to further strengthen access to biospecimens. The Tissue Procurement Core has implemented CaTISSUE to enhance the informatics infrastructure for Tissue Procurement, and is working to develop an approach to obtaining consent at the time of registration to the medical center, and link tissues with deidentified clinical data, that will further enhance the utility of tissue for HCCC investigators.

Public Health Relevance

The availability of human cancer and normal tissue is vital for basic and translational cancer research. The Tissue Procurement Core provides a centralized, efficient approach to providing this invaluable resource.

National Institute of Health (NIH)
National Cancer Institute (NCI)
Center Core Grants (P30)
Project #
Application #
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Iowa
Iowa City
United States
Zip Code
Mobley, Erin M; Foster, Kristin J; Terry, William W (2018) Identifying and Understanding the Gaps in Care Experienced by Adolescent and Young Adult Cancer Patients at the University of Iowa Hospitals and Clinics. J Adolesc Young Adult Oncol 7:592-603
Holahan, Heather M; Farah, Ronda S; Fitz, Sara et al. (2018) Health-related quality of life in patients with cutaneous T-cell lymphoma? Int J Dermatol 57:1314-1319
Kurth, Ann E; Krist, Alex H; Borsky, Amanda E et al. (2018) U.S. Preventive Services Task Force Methods to Communicate and Disseminate Clinical Preventive Services Recommendations. Am J Prev Med 54:S81-S87
Gadupudi, Gopi S; Elser, Benjamin A; Sandgruber, Fabian A et al. (2018) PCB126 Inhibits the Activation of AMPK-CREB Signal Transduction Required for Energy Sensing in Liver. Toxicol Sci 163:440-453
Strouse, Christopher; Mangalam, Ashutosh; Zhang, Jun (2018) Bugs in the system: bringing the human microbiome to bear in cancer immunotherapy. Gut Microbes :1-4
White, Katherine A; Swier, Vicki J; Cain, Jacob T et al. (2018) A porcine model of neurofibromatosis type 1 that mimics the human disease. JCI Insight 3:
Tota, Joseph E; Engels, Eric A; Madeleine, Margaret M et al. (2018) Risk of oral tongue cancer among immunocompromised transplant recipients and human immunodeficiency virus-infected individuals in the United States. Cancer 124:2515-2522
Davis, Lauren Z; Cuneo, Michaela; Thaker, Premal H et al. (2018) Changes in spiritual well-being and psychological outcomes in ovarian cancer survivors. Psychooncology 27:477-483
Pearson, Jennifer L; Amato, Michael S; Papandonatos, George D et al. (2018) Exposure to positive peer sentiment about nicotine replacement therapy in an online smoking cessation community is associated with NRT use. Addict Behav 87:39-45
Steinberg, Ryan L; Thomas, Lewis J; O'Donnell, Michael A (2018) Combination Intravesical Chemotherapy for Non-muscle-invasive Bladder Cancer. Eur Urol Focus 4:503-505

Showing the most recent 10 out of 1080 publications