Abstract

The aim of the Biostatistics and Informatics Core is to provide a variety of services that are targeted to enhance the scientific quality of cancer- related research at Washington University Medical Center.
Specific aims i nclude: providing biostatistical collaboration and consultation to Siteman Cancer Center (SCC) members at all stages of the research endeavor. While the bulk of this work involves the Clinical and Translational Research Program, there are other major active collaborations in the Prevention and Control Program, the Cancer Genetics Program and the Oncologic Imaging Program. The Biostatistics and Informatics Core also plays a strong consultative role with the developing Health Behavior Research, Hereditary Cancer and Pharmacology and the Clinical Trials, Small Animal Imaging and Multiplexed Gene Analysis Cores. provide biostatistical and methodological review of protocols submitted to the Protocol Review and Monitoring Committee (PRMC). providing biostatistical and methodological review of applications for the SCC intramural """"""""seed grant"""""""" program. providing informatics services, including the design and operation of web-based data entry systems. providing technical support for the SCC web present (www.siteman.wustl.edu/) including the interface to SCC databases.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA091842-02
Application #
6603621
Study Section
Subcommittee E - Prevention &Control (NCI)
Project Start
2002-07-01
Project End
2003-06-30
Budget Start
Budget End
Support Year
2
Fiscal Year
2002
Total Cost
Indirect Cost

  Institution

Name
Washington University
Department
Type
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130

  Publications

Groves, Andrew P; Gettinger, Katie; Druley, Todd E et al. (2018) Special Therapy and Psychosocial Needs Identified in a Multidisciplinary Cancer Predisposition Syndrome Clinic. J Pediatr Hematol Oncol :
Andley, Usha P; Tycksen, Eric; McGlasson-Naumann, Brittney N et al. (2018) Probing the changes in gene expression due to ?-crystallin mutations in mouse models of hereditary human cataract. PLoS One 13:e0190817
Sáenz, José B; Mills, Jason C (2018) Acid and the basis for cellular plasticity and reprogramming in gastric repair and cancer. Nat Rev Gastroenterol Hepatol 15:257-273
Miller, Christopher A; Tricarico, Christopher; Skidmore, Zachary L et al. (2018) A case of acute myeloid leukemia with promyelocytic features characterized by expression of a novel RARG-CPSF6 fusion. Blood Adv 2:1295-1299
Ostrander, Elizabeth L; Koh, Won Kyun; Mallaney, Cates et al. (2018) The GNASR201C mutation associated with clonal hematopoiesis supports transplantable hematopoietic stem cell activity. Exp Hematol 57:14-20
Jeong, Mira; Park, Hyun Jung; Celik, Hamza et al. (2018) Loss of Dnmt3a Immortalizes Hematopoietic Stem Cells In Vivo. Cell Rep 23:1-10
Trissal, Maria C; Wong, Terrence N; Yao, Juo-Chin et al. (2018) MIR142 Loss-of-Function Mutations Derepress ASH1L to Increase HOXA Gene Expression and Promote Leukemogenesis. Cancer Res 78:3510-3521
Copper, Tara Conway; Jeffe, Donna B; Ahmad, Fahd A et al. (2018) Emergency Information Forms for Children With Medical Complexity: A Qualitative Study. Pediatr Emerg Care :
Stephens, Calvin J; Kashentseva, Elena; Everett, William et al. (2018) Targeted in vivo knock-in of human alpha-1-antitrypsin cDNA using adenoviral delivery of CRISPR/Cas9. Gene Ther 25:139-156
Sharma, Piyush K; Dmitriev, Igor P; Kashentseva, Elena A et al. (2018) Development of an adenovirus vector vaccine platform for targeting dendritic cells. Cancer Gene Ther 25:27-38

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