Quantitative evaluation of research results is the foundation of much scientific research. The Biostatistics Core provides resources to assist in the planning, conduct and analysis of research in such a way that quantitative analyses are appropriate and illuminating. The core also assists in the dissemination of appropriate information both within and external to the Siteman Cancer Center (SCC). Services of the Biostatistics Core include: . Providing biostatistical and methodological review of all protocols submitted to the PRMC for full review. . Providing consultation during the design phase of protocols, including the selection of the appropriate study design, primary endpoints, sample size and statistical model. . Collaborating in the analysis of data collected for cancer-related protocols conducted by SCC members. The protocols range from analysis of large-scale outcomes research protocols to clinical trials to basic science data. . Consulting on the appropriate use of statistical models for all cancer-related studies conducted by SCC members. . Providing statistical and methodological review of all proposals submitted for SCC internal funding programs. . Providing statistical consultation to other SCC Cores with respect to their missions. Important links exit for the Health Behavior and Recruitment Core, the Clinical Trials Core, the Pharmacology Core, the Multiplexed Gene Analysis Core, the Small Animal Cancer Imaging Core and the Hereditary Cancer Core. . Providing informatics services in manipulation and merging of existing clinical electronic data sets. . Providing data entry systems to support the conduct of protocols requested by SCC investigators. . Providing access to the Barnes-Jewish Hospital cancer registry (maintained by Oncology Data Services) by means of a web-based interface for summary reports. . Providing web-based access to other SCC databases such as the PRMC registry of all cancer-related protocols. . Providing the infrastructure for the SCC website (www.siteman.wustl.edu/). . Providing consultation on the information systems technologies to be deployed by the SCC. . Providing email and other office automation resources to the SCC administrative unit. . Providing email list services to facilitate communication among members of SCC Programs and Focus Groups.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA091842-05
Application #
7117729
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2005-07-01
Budget End
2006-06-30
Support Year
5
Fiscal Year
2005
Total Cost
$202,031
Indirect Cost
Name
Washington University
Department
Type
DUNS #
068552207
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Olfson, Emily; Bloom, Joseph; Bertelsen, Sarah et al. (2018) CYP2A6 metabolism in the development of smoking behaviors in young adults. Addict Biol 23:437-447
Betleja, Ewelina; Nanjundappa, Rashmi; Cheng, Tao et al. (2018) A novel Cep120-dependent mechanism inhibits centriole maturation in quiescent cells. Elife 7:
Chen, Li-Shiun; Horton, Amy; Bierut, Laura (2018) Pathways to precision medicine in smoking cessation treatments. Neurosci Lett 669:83-92
Celik, Hamza; Koh, Won Kyun; Kramer, Ashley C et al. (2018) JARID2 Functions as a Tumor Suppressor in Myeloid Neoplasms by Repressing Self-Renewal in Hematopoietic Progenitor Cells. Cancer Cell 34:741-756.e8
Kabir, Ashraf Ul; Lee, Tae-Jin; Pan, Hua et al. (2018) Requisite endothelial reactivation and effective siRNA nanoparticle targeting of Etv2/Er71 in tumor angiogenesis. JCI Insight 3:
Hirbe, Angela C; Jennings, Jack; Saad, Nael et al. (2018) A Phase II Study of Tumor Ablation in Patients with Metastatic Sarcoma Stable on Chemotherapy. Oncologist 23:760-e76
Jenkins, Wiley D; Gilbert, David; Chen, Li-Shiun et al. (2018) Finding paths with the greatest chance of success: enabling and focusing lung cancer screening and cessation in resource-constrained areas. Transl Lung Cancer Res 7:S261-S264
Cherian, Mathew A; Olson, Sydney; Sundaramoorthi, Hemalatha et al. (2018) An activating mutation of interferon regulatory factor 4 (IRF4) in adult T-cell leukemia. J Biol Chem 293:6844-6858
Smith, Lee; Ae Lee, Jung; Mun, Junbae et al. (2018) Levels and patterns of self-reported and objectively-measured free-living physical activity among prostate cancer survivors: A prospective cohort study. Cancer :
Burclaff, Joseph; Mills, Jason C (2018) Plasticity of differentiated cells in wound repair and tumorigenesis, part II: skin and intestine. Dis Model Mech 11:

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