The Alvin J. Siteman Cancer Center (SCC) at Washington University School of Medicine and Barnes-Jewish Hospital was first designated as a Clinical Cancer Center in 2001, and as a Comprehensive Cancer Center in 2004. The SCC is composed of eight multidisciplinary research programs: Cancer &Developmental Biology, Tumor Immunology, Hematopoietic Development &Malignancy, Cellular Proliferation, Prevention & Control, Translational &Clinical Research, Oncologic Imaging, and the Breast Cancer Research Program. Research efforts in the programs are supported by 13 shared resources, two of which are under development: Embryonic Stem Cell Core;Tissue Procurement Core;Molecular and Genomic Analysis Core; Small Animal Cancer Imaging Core;High Speed Cell Sorter Core;Health Behavior, Communication and Outreach Core;Proteomics Core, Biomedical Informatics Core, Imaging Response Assessment Team, Biostatistics Core, Clinical Trials Core, High Throughput Screening Core (developing), and Dissemination & Implementation Core (developing). Since submission of the first Cancer Center Support Grant application in October 2000, the SCC has made significant progress. Overall cancer-related grant funding has increased nearly 100% to $152.8 million, and NCI funding has more than doubled to $55.2 million, while membership has increased only modestly to 270 research and research associate members. Interdisciplinary coordination and collaboration has been significantly enhanced through the full integration ofthe Genome Center (GC) in the SCO's research programs. Four key themes are used strategically to drive transdisciplinary research across the SCC - Cancer Genomics, Developmental Therapeutics, Novel/Molecular Diagnostics, and Dissemination and Implementation. Key indicators of progress include an increase in intra- and inter-programmatic publications to 31% in 2009;and an increase in the number of integrated, multidisciplinary, programmatic grants from 8 in 2000 to 17 in 2003, to 40 in 2009. This progress is directly attributable to a productive membership that is tightly focused on cancer research, research infrastructure strategically developed to meet the needs ofthe members, and engaged Senior Leaders who are committed to fostering collaborative, translational research.
The goals ofthe Siteman Cancer Center are to foster research productivity, promote interaction and collaboration, and take maximum advantage of institutional strengths and unique scientific opportunities to advance cancer diagnosis, treatment, and prevention for our patients.
|Burclaff, Joseph; Mills, Jason C (2018) Plasticity of differentiated cells in wound repair and tumorigenesis, part II: skin and intestine. Dis Model Mech 11:|
|Cherian, Mathew A; Olson, Sydney; Sundaramoorthi, Hemalatha et al. (2018) An activating mutation of interferon regulatory factor 4 (IRF4) in adult T-cell leukemia. J Biol Chem 293:6844-6858|
|Smith, Lee; Ae Lee, Jung; Mun, Junbae et al. (2018) Levels and patterns of self-reported and objectively-measured free-living physical activity among prostate cancer survivors: A prospective cohort study. Cancer :|
|Parikh, Rajiv P; Myckatyn, Terence M (2018) Paravertebral blocks and enhanced recovery after surgery protocols in breast reconstructive surgery: patient selection and perspectives. J Pain Res 11:1567-1581|
|Ekenga, Christine C; Pérez, Maria; Margenthaler, Julie A et al. (2018) Early-stage breast cancer and employment participation after 2 years of follow-up: A comparison with age-matched controls. Cancer 124:2026-2035|
|Lin, Huawen; Guo, Suyang; Dutcher, Susan K (2018) RPGRIP1L helps to establish the ciliary gate for entry of proteins. J Cell Sci 131:|
|Duan, Chong; Kallehauge, Jesper F; Pérez-Torres, Carlos J et al. (2018) Modeling Dynamic Contrast-Enhanced MRI Data with a Constrained Local AIF. Mol Imaging Biol 20:150-159|
|Zigler, Rachel E; Madden, Tessa; Ashby, Caitlin et al. (2018) Ulipristal Acetate for Unscheduled Bleeding in Etonogestrel Implant Users: A Randomized Controlled Trial. Obstet Gynecol 132:888-894|
|Murali, Bhavna; Ren, Qihao; Luo, Xianmin et al. (2018) Inhibition of the Stromal p38MAPK/MK2 Pathway Limits Breast Cancer Metastases and Chemotherapy-Induced Bone Loss. Cancer Res 78:5618-5630|
|Ahmad, Fahd A; Jeffe, Donna B; Plax, Katie et al. (2018) Characteristics of youth agreeing to electronic sexually transmitted infection risk assessment in the emergency department. Emerg Med J 35:46-51|
Showing the most recent 10 out of 1244 publications