The goal of the Cancer Imaging Program is to advance cancer research, diagnosis, and management bycarrying out novel research in multimodality anatomical and molecular imaging (MI). The ultimate goalis to introduce new multimodality imaging strategies into studies of molecular mechanisms, diagnosis,and treatments of cancer. The program is comprised of investigators whose work stems from sevenspecialty areas: imaging instrumentation/engineering, modeling/biostatistics, chemistry, molecularimaging assay development, cancer biology/proteomics, mouse models/small animal imaging/in vivoMI/therapeutic applications in cancer therapy, and clinical oncology. Research by program members hasresulted in a number of exciting findings, including new methods to image cancer gene therapy, methodsto study cell trafficking, new imaging probes for apoptosis, and novel breast cancer imaginginstrumentation. The Program adds value to the center by bringing biologists, chemists, engineers,radiologists, computational scientists, and clinical and translational researchers together to participate indeveloping innovative imaging tools and approaches. The 36 program members come from 11 School ofMedicine, School of Engineering, and School of Humanities & Sciences departments. Members are majorparticipants in one P50 program project, one R24 project, two U54 projects (one is an award in progress),two program project grants and three training grants. Direct cost funding in 2005 was $15.9 millionincluding $9 million in NCI research funding and $6.9 million in other peer reviewed funding. Membersgenerated 594 publications over the past six years, of which ~16% and ~11% were intra- and interprogrammaticcollaborations, respectively. Dr. Sam Gambhir, the Program leader, is a distinguishedphysician-scientist with an international reputation in molecular imaging and a laboratory program inmultimodality molecular imaging. Dr. Christopher Contag, Program co-leader, is an accomplishedscientist with major scientific contributions in the areas of stem cell biology, cancer imaging and tissueresponse to insult and is co-director of MIPS, and Faculty Advisor of the Cancer Imaging SharedResource. The leadership is united in its goals for program development to advance cancer imaging.
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