The Winship Cancer Institute of Emory University (Winship) is the only NCI-designated cancer center in Georgia, which is now the eighth most populous state and has the largest land area among states east of the Mississippi River. As the main tertiary cancer care and cancer research institution in the state, Winship has committed its four research programs as supported by its six shared resources to address the specific challenges associated with the cancer burden in Georgia. These challenges include: high tobacco usage and incidence of tobacco- related cancers; high proportion of cancer patients who are African American or black and/or have significant cancer disparity issues in their care, prognosis, and/or outcome; and low health literacy levels. Winship's mission is to lessen the burden of cancer for the citizens of Georgia, its primary catchment area. This will be accomplished by: (1) seeking greater insights into the molecular, genetic, and epigenetic basis of cancer; (2) discovering new knowledge that drives improvements in cancer detection, prevention, and/or therapy; (3) developing or defining novel therapeutic targets and/or agents as a pathway to better cancer therapies; and (4) studying and implementing population-based strategies to lessen the cancer burden in the state. The 164 Winship core members are actively engaged in one of four Winship research programs, all of which have a strong emphasis on transdisciplinary research: Cancer Cell Biology, Cancer Genetics and Epigenetics, Cancer Prevention and Control, and Discovery and Developmental Therapeutics. Winship's members are supported by six shared resources: Biostatistics and Bioinformatics Shared Resource, Cancer Animal Models Shared Resource, Cancer Tissue and Pathology Shared Resource, Emory Integrated Genomics Shared Resource, Emory Integrated Proteomics Shared Resource, and the Integrated Imaging Shared Resource; and two developing shared resources: Winship Research Informatics and Intervention Development, Dissemination, and Implementation Developing Shared Resources. Winship members are currently supported by $84.8M in total research funding (as of 3/31/2016) awarded via Emory University. Winship members Curran and Bruner serve as PIs on two NCI awards to the NRG Oncology Foundation for a total of $25.6M in support of clinical research infrastructure. Patient enrollment in Winship's interventional and non-interventional trials continues to increase, especially among patients from under-represented minority groups, and these activities have contributed to the FDA- approval of several novel anti-cancer agents during the present funding period. Winship has outstanding institutional commitment, with more than $200 million in institutional support committed over the next five years, a level almost twice that committed in 2011. Winship enjoys the same reporting line and organizational position as Emory's schools of medicine, public health, and nursing. Winship is uniquely positioned to apply its scientific strengths, outstanding membership, robust infrastructure, strong institutional support, and comprehensive training programs to fulfill its mission of lessening the burden of cancer on the state of Georgia and beyond.

Public Health Relevance

As the first and only NCI-designated cancer center in Georgia, the Winship Cancer Institute of Emory University (Winship) serves the state as its primary tertiary cancer care provider and its primary institution for cancer research, training, and education. Winship is an integral part of Emory University, coordinating the cancer specific research capabilities of the Emory University School of Medicine, Rollins School of Public Health, Nell Hodgson Woodruff School of Nursing, Emory College, and Emory Healthcare. Winship maintains direct responsibility to coordinate the clinical care provided to cancer patients and to oversee and coordinate the quality and multi- and trans-disciplinary nature of care with all relevant units to accomplish its mission to lessen the burden of cancer by aligning discovery and education with cancer prevention and cancer care.

National Institute of Health (NIH)
National Cancer Institute (NCI)
Center Core Grants (P30)
Project #
Application #
Study Section
Subcommittee I - Transistion to Independence (NCI)
Program Officer
He, Min
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Emory University
Schools of Medicine
United States
Zip Code
Mukherjee, Subhas; Tucker-Burden, Carol; Kaissi, Emily et al. (2018) CDK5 Inhibition Resolves PKA/cAMP-Independent Activation of CREB1 Signaling in Glioma Stem Cells. Cell Rep 23:1651-1664
Thompson, Jeffrey A; Christensen, Brock C; Marsit, Carmen J (2018) Methylation-to-Expression Feature Models of Breast Cancer Accurately Predict Overall Survival, Distant-Recurrence Free Survival, and Pathologic Complete Response in Multiple Cohorts. Sci Rep 8:5190
Sadigh, Gelareh; Holder, Chad A; Switchenko, Jeffrey M et al. (2018) Is there added value in obtaining cervical spine MRI in the assessment of nontraumatic angiographically negative subarachnoid hemorrhage? A retrospective study and meta-analysis of the literature. J Neurosurg 129:670-676
Allen, Samuel C; Lohani, Minisha; Hendershot, Kristopher A et al. (2018) Patient perspectives on compensation for biospecimen donation. AJOB Empir Bioeth 9:77-81
Cassidy, Richard J; Switchenko, Jeffrey M; Yushak, Melinda L et al. (2018) The importance of surgery in scalp angiosarcomas. Surg Oncol 27:A3-A8
Owonikoko, Taofeek K; Busari, Adeniyi K; Kim, Sungjin et al. (2018) Race-, Age-, and Gender-Based Characteristics and Toxicities of Targeted Therapies on Phase I Trials. Oncology 95:138-146
Koff, Jean L; Li, Jing-Xia; Zhang, Xinyan et al. (2018) Impact of the posttransplant lymphoproliferative disorder subtype on survival. Cancer 124:2327-2336
Dennison, Cori; King, Adrian R; Rutledge, Hannah et al. (2018) HPV Vaccine-Related Research, Promotion and Coordination in the State of Georgia: A Systematic Review. J Community Health :
Dhere, Vishal; Edelman, Scott; Waller, Edmund K et al. (2018) Myeloablative busulfan/cytoxan conditioning versus reduced-intensity fludarabine/melphalan conditioning for allogeneic hematopoietic stem cell transplant in patients with acute myelogenous leukemia. Leuk Lymphoma 59:837-843
Steuer, Conor E; Griffith, Christopher C; Nannapaneni, Sreenivas et al. (2018) A Correlative Analysis of PD-L1, PD-1, PD-L2, EGFR, HER2, and HER3 Expression in Oropharyngeal Squamous Cell Carcinoma. Mol Cancer Ther 17:710-716

Showing the most recent 10 out of 331 publications