The Cancer Center Biostatistics Shared Resource (BSR) functions as a centralized biostatistics and informatics support core and brings together expertise and intellectual resources campus-wide in biostatistics, clinical trials, bioinformatics, statistical genetics, epidemiology, and data management for all the Cancer Center investigators. BSR provides Cancer Center members with access to comprehensive biostatistics and bioinformatics expertise to ensure the statistical integrity, to optimize the experimental design and data analysis, and to extract and illuminate all relevant scientific and clinical information from the data. BSR biostatisticians play important integrated roles in each of the Cancer Center Scientific Programs and Disease Oriented Teams. Their significant contributions are reflected in both obtaining and sustaining major collaborative extramural research grants (SPORE, Center Grants, ROI's, and American Cancer Society grants) and publishing high-impact journal articles. These collaborations include: (1) As equal collaborators, BSR biostatisticians work on a large number of research projects of the Cancer Center's Scientific Programs and Disease Oriented Teams;(2) BSR biostatisticians serve as statistical reviewers on Cancer Center major committees (PRMC, DSMC, Clinical Cancer Research Committee and Pilot Awards Committee). (3) BSR biostatisticians provide education and training opportunities to clinical scholars and junior investigators through lectures and seminars;(4) BSR biostatisticians conduct statistical methodological research emerging from collaborative cancer research. In addition, BSR biostatisticians are also available for short term assistance on statistical analyses for Cancer Center members. The services of the Shared Resource are integrated with those of the Department of Clinical Sciences and NIH-funded Clinical and Translational Sciences Award (CTSA) to assure access to specialized expertise such as statistical genetics. Assistance is available on all types of research projects, ranging from clinical trials, basic science experiments, to epidemiological studies.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA142543-04
Application #
8519966
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2013-08-01
Budget End
2014-07-31
Support Year
4
Fiscal Year
2013
Total Cost
$140,094
Indirect Cost
$27,467
Name
University of Texas Sw Medical Center Dallas
Department
Type
DUNS #
800771545
City
Dallas
State
TX
Country
United States
Zip Code
75390
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Zhang, Shuyuan; Nguyen, Liem H; Zhou, Kejin et al. (2018) Knockdown of Anillin Actin Binding Protein Blocks Cytokinesis in Hepatocytes and Reduces Liver Tumor Development in Mice Without Affecting Regeneration. Gastroenterology 154:1421-1434
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Wang, Tao; Lu, Rong; Kapur, Payal et al. (2018) An Empirical Approach Leveraging Tumorgrafts to Dissect the Tumor Microenvironment in Renal Cell Carcinoma Identifies Missing Link to Prognostic Inflammatory Factors. Cancer Discov 8:1142-1155
LaRanger, Ryan; Peters-Hall, Jennifer R; Coquelin, Melissa et al. (2018) Reconstituting Mouse Lungs with Conditionally Reprogrammed Human Bronchial Epithelial Cells. Tissue Eng Part A 24:559-568
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Kim, Wanil; Shay, Jerry W (2018) Long-range telomere regulation of gene expression: Telomere looping and telomere position effect over long distances (TPE-OLD). Differentiation 99:1-9

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