Abstract

? MICROSCOPY SHARED RESOURCE Shared Resource Leader: Victor Friedrich, PhD The Tisch Cancer Institute (TCI) Microscopy Shared Resource Facility (MSRF) provides equipment, training, and expert consultation services for a full range of light microscopy applications, including confocal and multiphoton microscopes, four epi-fluorescence/brightfield systems, including structured illumination attachments, and software and workstations for deconvolution and other image processing, as well as image analysis. Two full time, masters-level engineers are present in the facility during regular hours to provide real time assistance to novice users. The high z-resolution and multichannel capabilities of the microscope systems are crucial for cancer studies involving immunofluorescence and fluorescent protein applications (e.g. localization of cell signaling and growth regulatory molecules, cell migration, and the effects of genetic and pharmacological manipulations on differentiation). The MSRF is comprised of the institutional Microscopy Shared Resource Facility and two TCI satellite sites that have been set up to better serve members of the Tisch Cancer Institute.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA196521-05
Application #
9754079
Study Section
Subcommittee I - Transistion to Independence (NCI)
Project Start
Project End
Budget Start
2019-08-01
Budget End
2020-07-31
Support Year
5
Fiscal Year
2019
Total Cost
Indirect Cost

  Institution

Name
Icahn School of Medicine at Mount Sinai
Department
Type
DUNS #
078861598
City
New York
State
NY
Country
United States
Zip Code
10029

  Publications

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Miller, Albert; Szeinuk, Jaime; Noonan, Curtis W et al. (2018) Libby Amphibole Disease: Pulmonary Function and CT Abnormalities in Vermiculite Miners. J Occup Environ Med 60:167-173
Vuong, Linh T; Iomini, Carlo; Balmer, Sophie et al. (2018) Kinesin-2 and IFT-A act as a complex promoting nuclear localization of ?-catenin during Wnt signalling. Nat Commun 9:5304
Bickell, Nina A; Lin, Jenny J; Abramson, Sarah R et al. (2018) Racial Disparities in Clinically Significant Prostate Cancer Treatment: The Potential Health Information Technology Offers. J Oncol Pract 14:e23-e33
Li, Weiqiang; Middha, Mridu; Bicak, Mesude et al. (2018) Genome-wide Scan Identifies Role for AOX1 in Prostate Cancer Survival. Eur Urol 74:710-719
Nobre, Ana Rita; Entenberg, David; Wang, Yarong et al. (2018) The Different Routes to Metastasis via Hypoxia-Regulated Programs. Trends Cell Biol 28:941-956
Zhang, Maomao; Di Martino, Julie S; Bowman, Robert L et al. (2018) Adipocyte-Derived Lipids Mediate Melanoma Progression via FATP Proteins. Cancer Discov 8:1006-1025
Leiter, Amanda; Bickell, Nina A; LeRoith, Derek et al. (2018) Statin Use and Breast Cancer Prognosis in Black and White Women. Horm Cancer 9:55-61

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