Abstract

The Tisch Cancer Institute (TCI) is geographically situated at the crossroads of some of New York City?s (NYC) wealthiest and poorest neighborhoods. Our immediate catchment area includes Central Harlem (CH), East Harlem (EH), the Upper East Side (UES) and the rescue and recovery workers of the World Trade Center (WTC). We choose these neighboring communities as they represent the epitome of cancer disparities and the challenges our nation faces in redressing them. Mount Sinai?s relationship with its Harlem and Upper East Side neighbors is a long-standing one, as seen by its community action boards, emphasis on URM training opportunities, and diverse workforce. TCI also conducts research on diseases relevant to the catchment area, as well community-engaging research that focuses on varying strategies to increase screening among minority populations and residents of public housing, improving treatment and reducing disparities.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA196521-06
Application #
10022666
Study Section
Subcommittee I - Transistion to Independence (NCI)
Project Start
2015-08-01
Project End
2025-07-31
Budget Start
2020-08-01
Budget End
2021-07-31
Support Year
6
Fiscal Year
2020
Total Cost
Indirect Cost

  Institution

Name
Icahn School of Medicine at Mount Sinai
Department
Type
DUNS #
078861598
City
New York
State
NY
Country
United States
Zip Code
10029

  Publications

Fujiwara, Naoto; Nakagawa, Hayato; Enooku, Kenichiro et al. (2018) CPT2 downregulation adapts HCC to lipid-rich environment and promotes carcinogenesis via acylcarnitine accumulation in obesity. Gut 67:1493-1504
Hogstad, Brandon; Berres, Marie-Luise; Chakraborty, Rikhia et al. (2018) RAF/MEK/extracellular signal-related kinase pathway suppresses dendritic cell migration and traps dendritic cells in Langerhans cell histiocytosis lesions. J Exp Med 215:319-336
Wu, Lisa M; Amidi, Ali; Tanenbaum, Molly L et al. (2018) Computerized cognitive training in prostate cancer patients on androgen deprivation therapy: a pilot study. Support Care Cancer 26:1917-1926
Chang, Sanders; Ru, Meng; Moshier, Erin L et al. (2018) The impact of radiation treatment planning technique on unplanned hospital admissions. Adv Radiat Oncol 3:647-654
Formenti, Silvia C; Rudqvist, Nils-Petter; Golden, Encouse et al. (2018) Radiotherapy induces responses of lung cancer to CTLA-4 blockade. Nat Med 24:1845-1851
Likhterov, Ilya; Ru, Meng; Ganz, Cindy et al. (2018) Objective and subjective hyposalivation after treatment for head and neck cancer: Long-term outcomes. Laryngoscope 128:2732-2739
Strub, Thomas; Ghiraldini, Flavia G; Carcamo, Saul et al. (2018) SIRT6 haploinsufficiency induces BRAFV600E melanoma cell resistance to MAPK inhibitors via IGF signalling. Nat Commun 9:3440
Sun, Zhen; Filipescu, Dan; Andrade, Joshua et al. (2018) Transcription-associated histone pruning demarcates macroH2A chromatin domains. Nat Struct Mol Biol 25:958-970
Kamath, Geetanjali R; Taioli, Emanuela; N Egorova, Natalia et al. (2018) Liver Cancer Disparities in New York City: A Neighborhood View of Risk and Harm Reduction Factors. Front Oncol 8:220
Buckstein, M; Rhome, R; Ru, M et al. (2018) Neoadjuvant chemoradiation radiation dose levels for surgically resectable esophageal cancer: predictors of use and outcomes. Dis Esophagus 31:

Showing the most recent 10 out of 143 publications