This is a renewal application for the Center for Drug Use and HIV Research. Our focus in this renewal will be """"""""From Discovery to Implementation and Back: Research Translation for the HIV/Substance (SU) Epidemic"""""""". Our current Center focused on interdisciplinary research related to HIV and substance use. During this period the Center experienced a growth in investigators (now located at 4 institutions) that provided new opportunities for synergy and collaboration, and investigators made many significant contributions to the field. However, HIV incidence, morbidity and mortality remain at unacceptably high rates, and substance use remains a critical barrier to reducing incidence and health disparities, accessing care, and maximizing the benefits of care. Substance users remain highly vulnerable and stigmatized, and a focus on the role of substance use in the epidemic is vital to our achieving the goals of the National HIV/AIDS Strategy (NHAS) (i.e., to reduce new infections, improve HIV-related health outcomes and reduce HIV-related health disparities). In addition, there is a need to expedite the research translation process (from discovery to public health impact) and to incorporate knowledge about the rapidly changing contexts that impact the epidemic, including biomedical advances and socio-economic changes. To create an infrastructure to address these challenges, we have made significant changes in our scope and Core structure for this renewal. The overarching aims of this Center renewal are to: (1) enhance the quality and impact of research to support the goals of the NHAS;(2) enhance projects'research translation efforts;and (3) enable projects to incorporate the study of the contextual changes influencing the HIV-substance use epidemic. We will achieve these aims through 6 Cores: an Administrative Core and 5 Research Support Cores: (1) Transdisciplinary Theoretical Synthesis and Development;(2) Infectious Diseases and Biomedical;(3) Transdisciplinary Research Methods;(4) Comparative Effectiveness Research;and (5) Pilot Projects and

Mentoring

These Cores will work to enhance synergy and productivity across investigators, and stimulate the development of new initiatives, new investigators and new knowledge to impact the HIV-substance use epidemic.

Public Health Relevance

Substance use remains a critical influence on the HIV epidemic, impacting incidence and compromising the benefits of HIV treatment. The Center provides a research infrastructure to enhance productivity and synergy across investigators working to meet the goals of the National HIV/AIDS Strategy. It will also enhance the research translation process so that findings are more rapidly brought from discovery to public health impact.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Center Core Grants (P30)
Project #
3P30DA011041-17S1
Application #
8784526
Study Section
Special Emphasis Panel (ZDA1-EXL-T (03))
Program Officer
Lambert, Elizabeth
Project Start
1999-04-15
Project End
2017-12-31
Budget Start
2014-01-01
Budget End
2014-12-31
Support Year
17
Fiscal Year
2014
Total Cost
$149,776
Indirect Cost
$53,654
Name
New York University
Department
Type
Schools of Nursing
DUNS #
041968306
City
New York
State
NY
Country
United States
Zip Code
10012
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Uusk├╝la, Anneli; Raag, Mait; Vorobjov, Sigrid et al. (2018) Another frontier for harm reduction: contraceptive needs of females who inject drugs in Estonia, a cross-sectional study. Harm Reduct J 15:10
Hautala, Dane; Abadie, Roberto; Thrash, Courtney et al. (2018) Latent Risk Subtypes Based on Injection and Sexual Behavior Among People Who Inject Drugs in Rural Puerto Rico. J Rural Health 34:236-245
Whitham, Hilary K; Sansom, Stephanie L; Wejnert, Cyprian et al. (2018) Sex Practices by HIV Awareness and Engagement in the Continuum of Care Among MSM: A National HIV Behavioral Surveillance Analysis in 21 U.S. Cities. AIDS Behav 22:840-847
Combellick, Joan L; Shin, Hakdong; Shin, Dongjae et al. (2018) Differences in the fecal microbiota of neonates born at home or in the hospital. Sci Rep 8:15660
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Palamar, Joseph J; Salomone, Alberto; Cleland, Charles M et al. (2018) Willingness to provide a hair sample for drug testing among electronic dance music party attendees. Subst Abus :1-8
Des Jarlais, Don C; Arasteh, K; Feelemyer, J et al. (2018) Hepatitis C virus prevalence and estimated incidence among new injectors during the opioid epidemic in New York City, 2000-2017: Protective effects of non-injecting drug use. Drug Alcohol Depend 192:74-79

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