This is a renewal application for the Center for Drug Use and HIV Research. Our focus in this renewal will be """"""""From Discovery to Implementation and Back: Research Translation for the HIV/Substance (SU) Epidemic"""""""". Our current Center focused on interdisciplinary research related to HIV and substance use. During this period the Center experienced a growth in investigators (now located at 4 institutions) that provided new opportunities for synergy and collaboration, and investigators made many significant contributions to the field. However, HIV incidence, morbidity and mortality remain at unacceptably high rates, and substance use remains a critical barrier to reducing incidence and health disparities, accessing care, and maximizing the benefits of care. Substance users remain highly vulnerable and stigmatized, and a focus on the role of substance use in the epidemic is vital to our achieving the goals of the National HIV/AIDS Strategy (NHAS) (i.e., to reduce new infections, improve HIV-related health outcomes and reduce HIV-related health disparities). In addition, there is a need to expedite the research translation process (from discovery to public health impact) and to incorporate knowledge about the rapidly changing contexts that impact the epidemic, including biomedical advances and socio-economic changes. To create an infrastructure to address these challenges, we have made significant changes in our scope and Core structure for this renewal. The overarching aims of this Center renewal are to: (1) enhance the quality and impact of research to support the goals of the NHAS;(2) enhance projects'research translation efforts;and (3) enable projects to incorporate the study of the contextual changes influencing the HIV-substance use epidemic. We will achieve these aims through 6 Cores: an Administrative Core and 5 Research Support Cores: (1) Transdisciplinary Theoretical Synthesis and Development;(2) Infectious Diseases and Biomedical;(3) Transdisciplinary Research Methods;(4) Comparative Effectiveness Research;and (5) Pilot Projects and
These Cores will work to enhance synergy and productivity across investigators, and stimulate the development of new initiatives, new investigators and new knowledge to impact the HIV-substance use epidemic.
Substance use remains a critical influence on the HIV epidemic, impacting incidence and compromising the benefits of HIV treatment. The Center provides a research infrastructure to enhance productivity and synergy across investigators working to meet the goals of the National HIV/AIDS Strategy. It will also enhance the research translation process so that findings are more rapidly brought from discovery to public health impact.
|Wolfson-Stofko, Brett; Gwadz, Marya V; Elliott, Luther et al. (2018) ""Feeling confident and equipped"": Evaluating the acceptability and efficacy of an overdose response and naloxone administration intervention to service industry employees in New York City. Drug Alcohol Depend 192:362-370|
|Palamar, Joseph J; Acosta, Patricia; Cleland, Charles M (2018) Attitudes and Beliefs About New Psychoactive Substance Use Among Electronic Dance Music Party Attendees. Subst Use Misuse 53:381-390|
|Williams, Leslie D; Kostaki, Evangelia-Georgia; Pavlitina, Eirini et al. (2018) Pockets of HIV Non-infection Within Highly-Infected Risk Networks in Athens, Greece. Front Microbiol 9:1825|
|Scheidell, Joy D; Quinn, Kelly; McGorray, Susan P et al. (2018) Childhood traumatic experiences and the association with marijuana and cocaine use in adolescence through adulthood. Addiction 113:44-56|
|Khan, Maria R; Scheidell, Joy D; Rosen, David L et al. (2018) Early age at childhood parental incarceration and STI/HIV-related drug use and sex risk across the young adult lifecourse in the US: Heightened vulnerability of black and Hispanic youth. Drug Alcohol Depend 183:231-239|
|Des Jarlais, D C; Cooper, H L F; Arasteh, K et al. (2018) Potential geographic ""hotspots"" for drug-injection related transmission of HIV and HCV and for initiation into injecting drug use in New York City, 2011-2015, with implications for the current opioid epidemic in the US. PLoS One 13:e0194799|
|Skaathun, Britt; Khanna, Aditya S; Morgan, Ethan et al. (2018) Network Viral Load: A Critical Metric for HIV Elimination. J Acquir Immune Defic Syndr 77:167-174|
|Palamar, Joseph J; Le, Austin; Cleland, Charles M (2018) Nonmedical opioid use among electronic dance music party attendees in New York City. Drug Alcohol Depend 186:226-232|
|Buchanan, Ashley L; Vermund, Sten H; Friedman, Samuel R et al. (2018) Assessing Individual and Disseminated Effects in Network-Randomized Studies. Am J Epidemiol 187:2449-2459|
|Khan, Bilal; Duncan, Ian; Saad, Mohamad et al. (2018) Combination interventions for Hepatitis C and Cirrhosis reduction among people who inject drugs: An agent-based, networked population simulation experiment. PLoS One 13:e0206356|
Showing the most recent 10 out of 339 publications