Five years ago, the Tufts Nutrition Collaborative - Center for Drug Abuse and AIDS Research (TNC-CDAAR) was funded by NIDA as just one of two CDAAR's in the nation. The CDAARs were charged with the following mission: to foster a collaborative approach to drug abuse and addiction research;to enable studies that would not occur without the climate, facilities, and resources that a research center can uniquely provide;to serve as a resource to attract established and promising investigators into drug abuse research; and to provide opportunities for research training, career development, and mentoring. The TNC-CDAAR was formed as a partnership between three East Coast Institutions (Tufts, Brown and Johns Hopkins) with a specific focus on studying nutritional and metabolic disorders among HIV-positive and HIV-negative drug users. Over the past five years, we have expanded the TNC-CDAAR to include collaborators from 3 international sites: Argentina, India, and Vietnam. Our major accomplishments, thus far, have been to 1) design and implement several new studies to assess and compare the prevalence and incidence of specific nutritional and metabolic disorders in drug users of different ethnicities, both in the U.S. and abroad;2) develop training materials, protocols, and manuals for investigators who want to undertake similar studies in their localities;3) help in the development of new grant proposals in Center-related areas of research;and 4) become a resource center on nutrition and metabolic disorders in drug users. Specifically, he Epidemiology and Biostatistics Core (Core F) will provide a wide range of services to Center Members to facilitate the design, collection, and analysis of nutritional and metabolic complications of HIV infection, recreational drug use, Hepatitis and liver disease among studies of injection drug users (IDUs) from the collaborating institutions. The major role of the Epidemiology and Biostatistics Core will be to increase the efficiency of data collection and analysis for Center Members at the collaborating institutions and to institute quality assurance procedures for all centralized data collected (See Section III below for listing of specific Core services). The Core will benefit from the expertise of two epidemiologists (Drs. Tang and Forrester) and a statistician (Dr. Terrin), all from Tufts University. Our team has worked together for several years on multiple cross-sectional and longitudinal datasets of drug users from Baltimore, Boston, and Providence. Dr. Terrin has developed models for longitudinal cohort studies to accommodate the inconsistent nature of drug use, allowing for the examination of use and duration of use for specific types of drugs on outcomes of interest.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Center Core Grants (P30)
Project #
5P30DA013868-09
Application #
8306306
Study Section
Special Emphasis Panel (ZDA1)
Project Start
Project End
Budget Start
2011-08-01
Budget End
2012-07-31
Support Year
9
Fiscal Year
2011
Total Cost
$238,420
Indirect Cost
Name
Tufts University
Department
Type
DUNS #
039318308
City
Boston
State
MA
Country
United States
Zip Code
02111
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Slama, Laurence; Jacobson, Lisa P; Li, Xiuhong et al. (2016) Longitudinal Changes Over 10 Years in Free Testosterone Among HIV-Infected and HIV-Uninfected Men. J Acquir Immune Defic Syndr 71:57-64
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Lambert, Allison A; Kirk, Gregory D; Astemborski, Jacquie et al. (2014) A cross sectional analysis of the role of the antimicrobial peptide cathelicidin in lung function impairment within the ALIVE cohort. PLoS One 9:e95099
Jordan, M R; Obeng-Aduasare, Y; Sheehan, H et al. (2014) Correlates of non-adherence to antiretroviral therapy in a cohort of HIV-positive drug users receiving antiretroviral therapy in Hanoi, Vietnam. Int J STD AIDS 25:662-668
Dugdale, Caitlin; Zaller, Nickolas; Bratberg, Jeffrey et al. (2014) Missed opportunities for HIV screening in pharmacies and retail clinics. J Manag Care Spec Pharm 20:339-45

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