The Computing Core will serve both basic scientists and clinical investigators who perform researchrelated to balance and hearing using animal models, balance in normal human subjects, and patients withbalance disorders. The overall goal of the Computing Core is to provide efficient and cost effectivecomputing support to a group of scientists who are independently funded in NIDCD mission areas.The Computing Core will support activities in multiple laboratories and shared facilities, primarily via theactivities of a scientific programmer who is an expert in real-time computing and scientific data analysis. Thelaboratories and facilities to be supported by the scientific programmer each perform research in an NIDCDmission area on either animal models or human subjects. Software will be developed and maintained fordelivering sensory stimuli, recording physiologic responses, and processing data. Animal research activitiesthat will make use of the services of the Computing Core will be performed in several facilities capable ofdelivering precise, computer-controlled physiologic stimulation and recording in the mammalian models.The laboratories that study human subjects that will be serviced by the Computing Core include: 1) aVirtual Environment Laboratory that consists of a projection-based immersive environment allowing control ofthe entire visual field while subjects stand on a fixed or moving surface, 2) a Human Vestibular Laboratoryconsisting of rotational devices and computerized posturography, and 3) a Vestibular PsychophysiologyLaboratory. The Computing Core is expected to facilitate additional new experiments that go beyond thecapabilities of the existing individual laboratories. The Computer Core will foster collaborative interactionsamong investigators with various backgrounds including bioengineering, and neurology.The Computing Core will occupy primarily a 100 square foot office in the Otolaryngology ResearchCenter in the Eye & Ear Institute for the Scientific Programmer. The Core Grant Director will manage theresources of the Core to assure appropriate resource allocation.
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