Administrative Structure Program Director, M. Charles Liberman, has 30 years of experience as an auditory neuroscientist, 25 years of continuous RO1 funding from the NIDCD, 8 years experience as PI of a PO1 grant entitled """"""""Basic and Clinical Studies of the Auditory System"""""""" which supported six collaborative projects among investigators at the Center, and 5 years experience as PI of this P30 Research Center. He was PI on one Shared Instrumentation grant (and co-Pi on another) which funded the acquisition of much of the major equipment powering the Imaging Core. He has been Director of the Eaton-Peabody Laboratory for 8 years and has co-authored collaborative research papers with 12 of the 23 participating Investigators in this Research Center over the last 5 years (Core Progress Report Summary, p. 112). Thus, he is familiar with all the research projects underway. The Program Director will be responsible for interacting with all Center Investigators and Core technical personnel to facilitate smooth operation of each Core. There will continue to be regular meetings of each Core group with the Program Director, and relevant Core Pl(s) to discuss past progress, overall operations, as well as to set future goals and priorities. For the Engineering Core, these meetings will continue to held on a monthly basis. For the Imaging and Histology/Surgery Cores, meetings will be held quarterly. These Core meetings will be open to all participating Investigators. Additional informal meetings will occur on an as needed basis. This type of overall structure has worked well over the past five years, as documented in the individual Core Progress Reports. Experience has shown that meetings of the Engineering Core need to be held more often than for the other two Cores, because there are more Core staffers in Engineering, thus there are more projects underway simultaneously. All Core technical personnel in all three Cores are required to track their time and effort allocations in Excel spreadsheet format. These spreadsheets are reviewed on at least a quarterly basis by the Program Director and individual Core Pis, to assess which Center Investigators are receiving investigator-specific services, and how the time allocation for investigator-specific requests are balanced by time spent on Core-wide projects. An overview of the balance of activities over the past five years in each of the Cores is given in the relevant Core Progress Reports. The Program Director will be assisted in the day-to day operations and in integration of the three Cores by an administrator, Dianna Sands. She has over 15 years experience working with the Program Director and as well as most of the participating investigators. She will be responsible for interacting with MEEI research administration to track grant expenditures for consumables, to allocate salary expenditures among appropriate cost centers, to track incoming orders to make sure they are appropriately routed, and to arrange meetings as needed. Administrator Sands, in turn, will be aided by an office assistant, who is salary is paid by the MEEI research administration budget. As a team, Ms. Sands and her assistant are also responsible for many aspects of pre-award and post-award grant administration for all other grants held by Center Investigators.

National Institute of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
Center Core Grants (P30)
Project #
Application #
Study Section
Special Emphasis Panel (ZDC1)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Massachusetts Eye and Ear Infirmary
United States
Zip Code
Currall, Benjamin B; Chen, Ming; Sallari, Richard C et al. (2018) Loss of LDAH associated with prostate cancer and hearing loss. Hum Mol Genet 27:4194-4203
Gao, Xue; Tao, Yong; Lamas, Veronica et al. (2018) Treatment of autosomal dominant hearing loss by in vivo delivery of genome editing agents. Nature 553:217-221
Francis, Nikolas A; Zhao, Wei; Guinan Jr, John J (2018) Auditory Attention Reduced Ear-Canal Noise in Humans by Reducing Subject Motion, Not by Medial Olivocochlear Efferent Inhibition: Implications for Measuring Otoacoustic Emissions During a Behavioral Task. Front Syst Neurosci 12:42
Hancock, Kenneth E; Chung, Yoojin; McKinney, Martin F et al. (2017) Temporal Envelope Coding by Inferior Colliculus Neurons with Cochlear Implant Stimulation. J Assoc Res Otolaryngol 18:771-788
Zuk, Nathaniel; Delgutte, Bertrand (2017) Neural coding of time-varying interaural time differences and time-varying amplitude in the inferior colliculus. J Neurophysiol 118:544-563
Berezina-Greene, Maria A; Guinan Jr, John J (2017) Electrically Evoked Medial Olivocochlear Efferent Effects on Stimulus Frequency Otoacoustic Emissions in Guinea Pigs. J Assoc Res Otolaryngol 18:153-163
Nam, Hui; Guinan Jr, John J (2017) Non-tip auditory-nerve responses that are suppressed by low-frequency bias tones originate from reticular lamina motion. Hear Res 358:1-9
Valero, M D; Burton, J A; Hauser, S N et al. (2017) Noise-induced cochlear synaptopathy in rhesus monkeys (Macaca mulatta). Hear Res 353:213-223
Kao, W Katherine; Gagnon, Patricia M; Vogel, Joseph P et al. (2017) Surface charge modification decreases Pseudomonas aeruginosa adherence in vitro and bacterial persistence in an in vivo implant model. Laryngoscope 127:1655-1661
Suzuki, Jun; Hashimoto, Ken; Xiao, Ru et al. (2017) Cochlear gene therapy with ancestral AAV in adult mice: complete transduction of inner hair cells without cochlear dysfunction. Sci Rep 7:45524

Showing the most recent 10 out of 169 publications