- Pilot and Feasibility Program The purpose of the Michigan Diabetes Research Center (MDRC) Pilot and Feasibility (P/F) Grants Program is to stimulate new research in the areas of diabetes, its complications, and related endocrine and metabolic disorders. This research may be in areas of basic biomedical science or clinical research. This program provides a minimum of $250,000 per year for P/F grant awards; additional funding may be provided for highly-rated applications using funds provided by the University of Michigan. The MDRC P/F program will fund two types of awards: (1) standard one-year $50,000 P/F awards with a single PI, and (2) two-year, $100,000 Diabetes Interdisciplinary Studies Program (DISP) awards that seek to support and promote new collaborations between two or more University of Michigan (UM) faculty members from distinct disciplines, to focus their combined research strengths on cutting-edge areas in diabetes research. Each year, the MDRC solicits applications for P/F and DISP grants from full-time instructional or research faculty at UM. Those eligible include: 1) new investigators without past or current NIH research support who are beginning careers in diabetes research, 2) established investigators who have not previously worked in diabetes research but wish to focus their expertise on diabetes, and 3) established diabetes investigators who propose innovative research in diabetes that represents a clear departure from their ongoing research. Highest priority is given to new investigators. Applications are actively solicited from across the university and are peer-reviewed by two or more extramural reviewers with expertise in the area of the application. Grant applications with the highest merit, as judged by this review process and the intramural Grants Program Advisory Council, receive awards. The balance of standard P/F and DISP awards may vary from year to year, depending upon the relative strength of applications for each award type. The ultimate goal of the program is to enable awardees to generate sufficient preliminary data to support a successful application for major research funding from the NIH or another national granting agency. The P/F Grants Program attracts investigators from diverse schools, departments, and institutes into diabetes research and fosters new, innovative, interdisciplinary, and collaborative diabetes research at UM.

National Institute of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Center Core Grants (P30)
Project #
Application #
Study Section
Special Emphasis Panel (ZDK1)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Michigan Ann Arbor
Ann Arbor
United States
Zip Code
Larkin, Daniel F P (2018) Letter to the Editor in Response to Kim et al, ""Effect of Histocompatibility Y Antigen Matching on Graft Survival in Primary Penetrating Keratoplasty."" Cornea 37:e29
Peck, Bailey C E; Seeley, Randy J (2018) How does 'metabolic surgery' work its magic? New evidence for gut microbiota. Curr Opin Endocrinol Diabetes Obes 25:81-86
Mitok, Kelly A; Freiberger, Elyse C; Schueler, Kathryn L et al. (2018) Islet proteomics reveals genetic variation in dopamine production resulting in altered insulin secretion. J Biol Chem 293:5860-5877
Rupp, Alan C; Allison, Margaret B; Jones, Justin C et al. (2018) Specific subpopulations of hypothalamic leptin receptor-expressing neurons mediate the effects of early developmental leptin receptor deletion on energy balance. Mol Metab :
Akama, Takeshi; Chun, Tae-Hwa (2018) Transcription factor 21 (TCF21) promotes proinflammatory interleukin 6 expression and extracellular matrix remodeling in visceral adipose stem cells. J Biol Chem 293:6603-6610
Peyrot, Mark; Dreon, Darlene; Zraick, Vivien et al. (2018) Patient Perceptions and Preferences for a Mealtime Insulin Delivery Patch. Diabetes Ther 9:297-307
Guo, Huan; Sun, Jinhong; Li, Xin et al. (2018) Positive charge in the n-region of the signal peptide contributes to efficient post-translational translocation of small secretory preproteins. J Biol Chem 293:1899-1907
Flannick, Jason (see original citation for additional authors) (2018) Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls. Sci Data 5:180002
Huang, Chao; Fisher, Kiera P; Hammer, Sandra S et al. (2018) Plasma Exosomes Contribute to Microvascular Damage in Diabetic Retinopathy by Activating the Classical Complement Pathway. Diabetes 67:1639-1649
Ge, C; Mohamed, F; Binrayes, A et al. (2018) Selective Role of Discoidin Domain Receptor 2 in Murine Temporomandibular Joint Development and Aging. J Dent Res 97:321-328

Showing the most recent 10 out of 1823 publications