The mission of the MDRC is to promote new discoveries and enhance scientific progress through the support of cutting-edge basic and clinical research by its highly interactive research base. The MDRC research base comprises 145 members: 118 members with $56.8 million of annual direct cost diabetes-related funding at the University of Michigan (UM) along with 27 regional members with $8.6 million of annual funding at three nearby Regional Partner Institutions: Michigan State University (MSU), Wayne State University (WSU) and the University of Toledo (UT). The investigators that make up the MDRC research base perform ground-breaking research in five broad areas relevant to diabetes: Cellular Aspects of Diabetes and Metabolism; Integrative Aspects of Diabetes and Metabolism; Islet Biology; Diabetic Complications; and Clinical Research in Diabetes and Metabolism. To support and empower research by its members, the MDRC will: 1. Coordinate activities that raise awareness of, interest in, and support for basic and translational research in diabetes, its complications, and related endocrine and metabolic disorders at the University of Michigan and beyond. 2. Advance learning and promote scientific exchange related to diabetes, endocrinology and metabolism. 3. Provide research cores that provide shared, specialized technical resources and expertise that enhance the efficiency, productivity, and multidisciplinary nature of research performed by MDRC investigators. 4. Support a Pilot and Feasibility studies grant program. 5. Provide support for research in diabetes, its complications, and related endocrine and metabolic disorders at Regional Partner Institutions. The MDRC provides membership, enrichment activities, an expanded Pilot and Feasibility Grant Program, and access to the MDRC Molecular Genetics Core for researchers at Regional Partner Institutions who study diabetes, its complications, and related endocrine and metabolic disorders.

Public Health Relevance

? MDRC Center Overview The MDRC oversees and provides research cores, enrichment activities and pilot and feasibility grants programs to promote new discoveries and enhance scientific progress through the support of cutting-edge basic and clinical research by its highly interactive research base, which comprises 145 members at the University of Michigan and regional partner institutions (Michigan State University (MSU), Wayne State University (WSU) and the University of Toledo (UT).

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK020572-44
Application #
10071159
Study Section
Special Emphasis Panel (ZDK1)
Program Officer
Silva, Corinne M
Project Start
1996-12-01
Project End
2022-11-30
Budget Start
2020-12-01
Budget End
2021-11-30
Support Year
44
Fiscal Year
2021
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Sujkowski, Alyson; Wessells, Robert (2018) Using Drosophila to Understand Biochemical and Behavioral Responses to Exercise. Exerc Sport Sci Rev 46:112-120
Brown, Rebecca J; Oral, Elif A; Cochran, Elaine et al. (2018) Long-term effectiveness and safety of metreleptin in the treatment of patients with generalized lipodystrophy. Endocrine 60:479-489
Lee, Pearl G; Damschroder, Laura J; Holleman, Robert et al. (2018) Older Adults and Diabetes Prevention Programs in the Veterans Health Administration. Diabetes Care 41:2644-2647
Spencer, Michael S; Kieffer, Edith C; Sinco, Brandy et al. (2018) Outcomes at 18 Months From a Community Health Worker and Peer Leader Diabetes Self-Management Program for Latino Adults. Diabetes Care 41:1414-1422
Ramos, Carla J; Lin, Chengmao; Liu, Xuwen et al. (2018) The EPAC-Rap1 pathway prevents and reverses cytokine-induced retinal vascular permeability. J Biol Chem 293:717-730
Ma, Fuqiang; Chung, Meng Ting; Yao, Yuan et al. (2018) Efficient molecular evolution to generate enantioselective enzymes using a dual-channel microfluidic droplet screening platform. Nat Commun 9:1030
Pieber, Thomas R; Marso, Steven P; McGuire, Darren K et al. (2018) DEVOTE 3: temporal relationships between severe hypoglycaemia, cardiovascular outcomes and mortality. Diabetologia 61:58-65
McEwen, Laura N; Lee, Pearl G; Backlund, Jye-Yu C et al. (2018) Recording of Diabetes on Death Certificates of Decedents With Type 1 Diabetes in DCCT/EDIC. Diabetes Care 41:e158-e160
Klueh, Ulrike; Ludzinska, Izabela; Czajkowski, Caroline et al. (2018) Crosslinked basement membrane-based coatings enhance glucose sensor function and continuous glucose monitoring in vivo. J Biomed Mater Res A 106:7-16
Park, Min-Jung; Iyer, Sapna; Xue, Xiang et al. (2018) HIF1-alpha Regulates Acinar Cell Function and Response to Injury in Mouse Pancreas. Gastroenterology 154:1630-1634.e3

Showing the most recent 10 out of 1823 publications