? Expanded (Regional) Pilot and Feasibility Program The specific aim of the Michigan Diabetes Research Center (MDRC) expanded Regional Pilot/Feasibility Study (P/F) Grants Program is to stimulate new research and collaboration in the areas of diabetes, its complications and related endocrine and metabolic disorders in the region. This research may be in areas of basic biomedical science or clinical research. This program will fund at least 2 P/F grants submitted by investigators from our three regional partners per year. A minimum of $100,000 per year will be provided by the MDRC and a minimum of an additional $20,000 per year will be provided through cost-sharing agreements with the University of Toledo, Michigan State University, and Wayne State University. Each year, the MDRC will solicit applications for grants from full-time instructional or research faculty at these three institutions. Those eligible include: 1) new investigators without current or past NIH research support who are beginning careers in diabetes research, 2) established investigators new to diabetes research who wish to focus their expertise on diabetes, and 3) established investigators who propose innovative research in diabetes that represents a clear departure from their ongoing research. Applications are peer-reviewed by at least two extramural investigators with expertise in the area of the application. Those with merit, as judged by this review process and the Grants Program Advisory Council, which includes representatives from the three regional partner universities, will receive P/F awards. The ultimate goal of the grant program is to enhance communication and collaboration among regional diabetes researchers, accelerate the pace of research, and enable awardees to generate sufficient preliminary data for successful applications for major research funding from the NIH or other national granting agencies.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK020572-44
Application #
10071184
Study Section
Special Emphasis Panel (ZDK1)
Project Start
1996-12-01
Project End
2022-11-30
Budget Start
2020-12-01
Budget End
2021-11-30
Support Year
44
Fiscal Year
2021
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Type
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Vollbrecht, Peter J; Nesbitt, Kathryn M; Mabrouk, Omar S et al. (2018) Cocaine and desipramine elicit distinct striatal noradrenergic and behavioral responses in selectively bred obesity-resistant and obesity-prone rats. Behav Brain Res 346:137-143
Ryan, Karen K; Packard, Amy E B; Larson, Karlton R et al. (2018) Dietary Manipulations That Induce Ketosis Activate the HPA Axis in Male Rats and Mice: A Potential Role for Fibroblast Growth Factor-21. Endocrinology 159:400-413
Liu, Jeffrey M H; Zhang, Xiaomin; Joe, Shelby et al. (2018) Evaluation of biomaterial scaffold delivery of IL-33 as a localized immunomodulatory agent to support cell transplantation in adipose tissue. J Immunol Regen Med 1:1-12
Rao, Xiaoquan; Zhong, Jixin; Brook, Robert D et al. (2018) Effect of Particulate Matter Air Pollution on Cardiovascular Oxidative Stress Pathways. Antioxid Redox Signal 28:797-818
Mahajan, Anubha; Taliun, Daniel; Thurner, Matthias et al. (2018) Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps. Nat Genet 50:1505-1513
Banu, Sakhila K; Stanley, Jone A; Taylor, Robert J et al. (2018) Sexually Dimorphic Impact of Chromium Accumulation on Human Placental Oxidative Stress and Apoptosis. Toxicol Sci 161:375-387
Jun, Heejin; Yu, Hui; Gong, Jianke et al. (2018) An immune-beige adipocyte communication via nicotinic acetylcholine receptor signaling. Nat Med 24:814-822
Douros, Jonathan D; Lewis, Alfor G; Smith, Eric P et al. (2018) Enhanced Glucose Control Following Vertical Sleeve Gastrectomy Does Not Require a ?-Cell Glucagon-Like Peptide 1 Receptor. Diabetes 67:1504-1511
O'Rourke, Robert W (2018) Adipose tissue and the physiologic underpinnings of metabolic disease. Surg Obes Relat Dis 14:1755-1763
Zhang, Kezhong; Kim, Hyunbae; Fu, Zhiyao et al. (2018) Deficiency of the Mitochondrial NAD Kinase Causes Stress-Induced Hepatic Steatosis in Mice. Gastroenterology 154:224-237

Showing the most recent 10 out of 1823 publications