Abstract

The Imaging Core is dedicated to providing HDDC investigators and their trainees with accessto a variety of imaging methods for analysis of tissue, cellular and subcellular structure. Themethodologies offered by Imaging Core Scientists strongly emphasize the integration of structural,functional and biochemical information. The Core is particularly oriented toward education of Centerscientists and their trainees in the competent and critical application of high-resolution microscopicmethods such as light, confocal and deconvolution microscopy (including live cell capabilities), electronmicroscopy, immunocytochemistry, microfluorimetry and electronic or photographic presentation of highquality structural data.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
2P30DK034854-21A1
Application #
7001915
Study Section
Special Emphasis Panel (ZDK1-GRB-8 (M1))
Project Start
2005-12-01
Project End
2010-11-30
Budget Start
2005-12-01
Budget End
2006-11-30
Support Year
21
Fiscal Year
2006
Total Cost
$305,504
Indirect Cost

  Institution

Name
Children's Hospital Boston
Department
Type
DUNS #
076593722
City
Boston
State
MA
Country
United States
Zip Code
02115

  Publications

Zhang, Sicai; Lebreton, Francois; Mansfield, Michael J et al. (2018) Identification of a Botulinum Neurotoxin-like Toxin in a Commensal Strain of Enterococcus faecium. Cell Host Microbe 23:169-176.e6
Ouahed, Jodie; Gordon, William; Canavan, James B et al. (2018) Mucosal Gene Expression in Pediatric and Adult Patients With Ulcerative Colitis Permits Modeling of Ideal Biopsy Collection Strategy for Transcriptomic Analysis. Inflamm Bowel Dis 24:2565-2578
Kumar, Nitin; Abu Dayyeh, Barham K; Lopez-Nava Breviere, Gontrand et al. (2018) Endoscopic sutured gastroplasty: procedure evolution from first-in-man cases through current technique. Surg Endosc 32:2159-2164
Sabatos-Peyton, Catherine A; Nevin, James; Brock, Ansgar et al. (2018) Blockade of Tim-3 binding to phosphatidylserine and CEACAM1 is a shared feature of anti-Tim-3 antibodies that have functional efficacy. Oncoimmunology 7:e1385690
Mina, Amir I; LeClair, Raymond A; LeClair, Katherine B et al. (2018) CalR: A Web-Based Analysis Tool for Indirect Calorimetry Experiments. Cell Metab 28:656-666.e1
Luong, Phi; Hedl, Matija; Yan, Jie et al. (2018) INAVA-ARNO complexes bridge mucosal barrier function with inflammatory signaling. Elife 7:
Nudel, K; Zhao, X; Basu, S et al. (2018) Genomics of Corynebacterium striatum, an emerging multidrug-resistant pathogen of immunocompromised patients. Clin Microbiol Infect 24:1016.e7-1016.e13
Biswas, Amlan; Shouval, Dror S; Griffith, Alexandra et al. (2018) WASP-mediated regulation of anti-inflammatory macrophages is IL-10 dependent and is critical for intestinal homeostasis. Nat Commun 9:1779
Han, Lichy; Maciejewski, Mateusz; Brockel, Christoph et al. (2018) A probabilistic pathway score (PROPS) for classification with applications to inflammatory bowel disease. Bioinformatics 34:985-993
Fishman, Laurie N; Kearney, Jennifer; DeGroote, Maya et al. (2018) Creation of Experience-based Celiac Benchmarks: The First Step in Pretransition Self-management Assessment. J Pediatr Gastroenterol Nutr 67:e6-e10

Showing the most recent 10 out of 869 publications