Abstract

application) The specific aims of the Gnotobiotic Core are 1. to provide germ-free or gnotobiotic rodents and conventional controls to center members as first priority, but to also provide these unique resources to investigators around the world; 2. to establish new genetic stocks and strains of rodents in an axenic, gnotobiotic or conventional status as required by research projects; 3. to provide technical assistance and isolators to maintain axenic and gnotobiotic rodent models; 4. to provide technical assistance to maintain control animals free of disease and inoculated with various gut microbiotas;5. to provide specific pathogen free conditions for maintaining production of a variety of genetically engineered rodents.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
2P30DK034987-15
Application #
6316580
Study Section
Project Start
2000-06-01
Project End
2000-11-30
Budget Start
Budget End
Support Year
15
Fiscal Year
2000
Total Cost
$333,334
Indirect Cost

  Institution

Name
University of North Carolina Chapel Hill
Department
Type
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599

  Publications

Kochar, Bharati; Barnes, Edward L; Long, Millie D et al. (2018) Depression Is Associated With More Aggressive Inflammatory Bowel Disease. Am J Gastroenterol 113:80-85
Tappata, Manaswita; Eluri, Swathi; Perjar, Irina et al. (2018) Association of mast cells with clinical, endoscopic, and histologic findings in adults with eosinophilic esophagitis. Allergy 73:2088-2092
Schulfer, Anjelique F; Battaglia, Thomas; Alvarez, Yelina et al. (2018) Intergenerational transfer of antibiotic-perturbed microbiota enhances colitis in susceptible mice. Nat Microbiol 3:234-242
Dong, Jing; Buas, Matthew F; Gharahkhani, Puya et al. (2018) Determining Risk of Barrett's Esophagus and Esophageal Adenocarcinoma Based on Epidemiologic Factors and Genetic Variants. Gastroenterology 154:1273-1281.e3
Azcarate-Peril, M Andrea; Butz, Natasha; Cadenas, Maria Belen et al. (2018) An Attenuated Salmonella enterica Serovar Typhimurium Strain and Galacto-Oligosaccharides Accelerate Clearance of Salmonella Infections in Poultry through Modifications to the Gut Microbiome. Appl Environ Microbiol 84:
Carlson, Alexander L; Xia, Kai; Azcarate-Peril, M Andrea et al. (2018) Infant Gut Microbiome Associated With Cognitive Development. Biol Psychiatry 83:148-159
Lee, Mi Kyeong; Carnes, Megan U; Butz, Natasha et al. (2018) Exposures Related to House Dust Microbiota in a U.S. Farming Population. Environ Health Perspect 126:067001
Evon, D M; Amador, J; Stewart, P et al. (2018) Psychometric properties of the PROMIS short form measures in a U.S. cohort of 961 patients with chronic hepatitis C prescribed direct acting antiviral therapy. Aliment Pharmacol Ther 47:1001-1011
Jones, Roshonda B; Fodor, Anthony A; Peery, Anne F et al. (2018) An Aberrant Microbiota is not Strongly Associated with Incidental Colonic Diverticulosis. Sci Rep 8:4951
Busch, Evan L; Galanko, Joseph A; Sandler, Robert S et al. (2018) Lifestyle Factors, Colorectal Tumor Methylation, and Survival Among African Americans and European Americans. Sci Rep 8:9470

Showing the most recent 10 out of 944 publications