Abstract

application) This core in the previous funded period was the Immunoassay Core. The objectives of this core is to provide the investigators 1. with convenient and accurate RIA, ELISA, or Western blot analyses; 2. the opportunity to generate new antibodies or immunoassays that are not commercially available; 3. the option of rigorously evaluating the specificity of any immunoassay with a battery of supplementary biochemical analyses, including HPLC characterization and or Western blotting of antigen-containing extracts, and 4. the capability to use antigenic determinants to generate pure populations of cells for direct analysis, or for further study in conjunction with the tissue culture capabilities of the Advanced Cell Technologies (ACT) core.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
2P30DK034987-15
Application #
6316582
Study Section
Project Start
2000-06-01
Project End
2000-11-30
Budget Start
Budget End
Support Year
15
Fiscal Year
2000
Total Cost
$333,334
Indirect Cost

  Institution

Name
University of North Carolina Chapel Hill
Department
Type
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599

  Publications

Kochar, Bharati; Barnes, Edward L; Long, Millie D et al. (2018) Depression Is Associated With More Aggressive Inflammatory Bowel Disease. Am J Gastroenterol 113:80-85
Tappata, Manaswita; Eluri, Swathi; Perjar, Irina et al. (2018) Association of mast cells with clinical, endoscopic, and histologic findings in adults with eosinophilic esophagitis. Allergy 73:2088-2092
Schulfer, Anjelique F; Battaglia, Thomas; Alvarez, Yelina et al. (2018) Intergenerational transfer of antibiotic-perturbed microbiota enhances colitis in susceptible mice. Nat Microbiol 3:234-242
Dong, Jing; Buas, Matthew F; Gharahkhani, Puya et al. (2018) Determining Risk of Barrett's Esophagus and Esophageal Adenocarcinoma Based on Epidemiologic Factors and Genetic Variants. Gastroenterology 154:1273-1281.e3
Azcarate-Peril, M Andrea; Butz, Natasha; Cadenas, Maria Belen et al. (2018) An Attenuated Salmonella enterica Serovar Typhimurium Strain and Galacto-Oligosaccharides Accelerate Clearance of Salmonella Infections in Poultry through Modifications to the Gut Microbiome. Appl Environ Microbiol 84:
Carlson, Alexander L; Xia, Kai; Azcarate-Peril, M Andrea et al. (2018) Infant Gut Microbiome Associated With Cognitive Development. Biol Psychiatry 83:148-159
Lee, Mi Kyeong; Carnes, Megan U; Butz, Natasha et al. (2018) Exposures Related to House Dust Microbiota in a U.S. Farming Population. Environ Health Perspect 126:067001
Evon, D M; Amador, J; Stewart, P et al. (2018) Psychometric properties of the PROMIS short form measures in a U.S. cohort of 961 patients with chronic hepatitis C prescribed direct acting antiviral therapy. Aliment Pharmacol Ther 47:1001-1011
Jones, Roshonda B; Fodor, Anthony A; Peery, Anne F et al. (2018) An Aberrant Microbiota is not Strongly Associated with Incidental Colonic Diverticulosis. Sci Rep 8:4951
Busch, Evan L; Galanko, Joseph A; Sandler, Robert S et al. (2018) Lifestyle Factors, Colorectal Tumor Methylation, and Survival Among African Americans and European Americans. Sci Rep 8:9470

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