Abstract

The mission ofthe Center for Gastrointestinal Biology and Disease is to promote and enhance multidisciplinary digestive disease research. The center achieves this purpose through: ? Core laboratories that provide training, technical support, laboratory animals, reagents, and/or assays, ? A pilot/feasibility program that offers startup funds to junior investigators, or to established investigators who wish to pursue new directions in research, ? A scientific enrichment program.-- consisting of seminars, lectures by visiting scientists, workshops and research competitions for trainees ~ that improves the intellectual climate for gastrointestinal biological research, and promotes cooperation, collaboration and communication among involved personnel, and ? A professional development and training program that promotes the development of junior faculty and trainees.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK034987-29
Application #
8576455
Study Section
Special Emphasis Panel (ZDK1-GRB-8)
Project Start
Project End
Budget Start
2013-12-01
Budget End
2014-11-30
Support Year
29
Fiscal Year
2014
Total Cost
$566,158
Indirect Cost
$129,427

  Institution

Name
University of North Carolina Chapel Hill
Department
Type
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599

  Publications

Rolston, Vineet S; Boroujerdi, Laleh; Long, Millie D et al. (2018) The Influence of Hormonal Fluctuation on Inflammatory Bowel Disease Symptom Severity-A Cross-Sectional Cohort Study. Inflamm Bowel Dis 24:387-393
Eaton, Kathryn; Pirani, Ali; Snitkin, Evan S et al. (2018) Replication Study: Intestinal inflammation targets cancer-inducing activity of the microbiota. Elife 7:
Dong, Jing; Levine, David M; Buas, Matthew F et al. (2018) Interactions Between Genetic Variants and Environmental Factors Affect Risk of Esophageal Adenocarcinoma and Barrett's Esophagus. Clin Gastroenterol Hepatol 16:1598-1606.e4
Truax, Agnieszka D; Chen, Liang; Tam, Jason W et al. (2018) The Inhibitory Innate Immune Sensor NLRP12 Maintains a Threshold against Obesity by Regulating Gut Microbiota Homeostasis. Cell Host Microbe 24:364-378.e6
Palacios, Michelle; Miner, Taryn A; Frederick, Daniel R et al. (2018) Identification of Two Regulators of Virulence That Are Conserved in Klebsiella pneumoniae Classical and Hypervirulent Strains. MBio 9:
Williamson, Ian A; Arnold, Jason W; Samsa, Leigh Ann et al. (2018) A High-Throughput Organoid Microinjection Platform to Study Gastrointestinal Microbiota and Luminal Physiology. Cell Mol Gastroenterol Hepatol 6:301-319
Zhang, Cun-Jin; Wang, Chenhui; Jiang, Meiling et al. (2018) Act1 is a negative regulator in T and B cells via direct inhibition of STAT3. Nat Commun 9:2745
Evon, Donna M; Golin, Carol E; Ruffin, Rachel et al. (2018) Novel patient-reported outcomes (PROs) used in a pilot and feasibility study of a Cognitive Behavioral Coping Skills (CBCS) group intervention for patients with chronic hepatitis C. Pilot Feasibility Stud 4:92
Busch, Evan L; Don, Prabhani Kuruppumullage; Chu, Haitao et al. (2018) Diagnostic accuracy and prediction increment of markers of epithelial-mesenchymal transition to assess cancer cell detachment from primary tumors. BMC Cancer 18:82
Herfarth, Hans; Barnes, Edward L; Valentine, John F et al. (2018) Methotrexate Is Not Superior to Placebo in Maintaining Steroid-Free Response or Remission in Ulcerative Colitis. Gastroenterology 155:1098-1108.e9

Showing the most recent 10 out of 944 publications