The objectives of the Clinical Core have not changed since its initial proposal. The overarching goal of the Clinical Core is to facilitate translations! and patient-oriented research. The Clinical Translational Core aims to develop an infrastructure for patient-oriented research by streamlining regulatory compliance, attaining high-quality samples linked to large clinical phenotypic information through integration of diverse databases and, innovative application of statistical tools.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK034989-28
Application #
8305631
Study Section
Special Emphasis Panel (ZDK1)
Project Start
Project End
Budget Start
2011-09-01
Budget End
2012-08-31
Support Year
28
Fiscal Year
2011
Total Cost
$3
Indirect Cost
Name
Yale University
Department
Type
DUNS #
043207562
City
New Haven
State
CT
Country
United States
Zip Code
06520
Sachar, Hamita; Pichetshote, Nipaporn; Nandigam, Kavitha et al. (2018) Continued midazolam versus diphenhydramine in difficult-to-sedate patients: a randomized double-blind trial. Gastrointest Endosc 87:1297-1303
Bhutta, A Q; Garcia-Tsao, G; Reddy, K R et al. (2018) Beta-blockers in hospitalised patients with cirrhosis and ascites: mortality and factors determining discontinuation and reinitiation. Aliment Pharmacol Ther 47:78-85
Kuo, Andrew; Lee, Monica Y; Yang, Kui et al. (2018) Caveolin-1 regulates lipid droplet metabolism in endothelial cells via autocrine prostacyclin-stimulated, cAMP-mediated lipolysis. J Biol Chem 293:973-983
Hollister, Kristin; Kusumanchi, Praveen; Ross, Ruth Ann et al. (2018) Levels of circulating follicular helper T cells, T helper 1 cells, and the prognostic significance of soluble form of CD40 ligand on survival in patients with alcoholic cirrhosis. Liver Res 2:52-59
Garcia-Tsao, Guadalupe (2018) Management of Acute Variceal Hemorrhage as a Model of Individualized Care for Patients With Cirrhosis. Clin Gastroenterol Hepatol 16:24-26
Fonseca, Matheus de Castro; França, Andressa; Florentino, Rodrigo Machado et al. (2018) Cholesterol-enriched membrane microdomains are needed for insulin signaling and proliferation in hepatic cells. Am J Physiol Gastrointest Liver Physiol 315:G80-G94
Chang, Binxia; Hao, Shuli; Zhang, Longyu et al. (2018) Association Between Aldehyde Dehydrogenase 2 Glu504Lys Polymorphism and Alcoholic Liver Disease. Am J Med Sci 356:10-14
Sullivan, Rebecca; Abraham, Alice; Simpson, Christine et al. (2018) Three-Month Randomized Clinical Trial of Nasal Calcitonin in Adults with X-linked Hypophosphatemia. Calcif Tissue Int 102:666-670
Ouyang, Xinshou; Han, Sheng-Na; Zhang, Ji-Yuan et al. (2018) Digoxin Suppresses Pyruvate Kinase M2-Promoted HIF-1? Transactivation in Steatohepatitis. Cell Metab 27:339-350.e3
Chen, Yonglin; Ouyang, Xinshou; Hoque, Rafaz et al. (2018) ?-Hydroxybutyrate protects from alcohol-induced liver injury via a Hcar2-cAMP dependent pathway. J Hepatol 69:687-696

Showing the most recent 10 out of 763 publications