The major goal of the Clinical Nutrition Research Unit (CNRU) at the University of Washington is to promote and enhance interdisciplinary nutrition research by bringing together basic science and clinical investigators on a cooperative basis. Because of the multidisciplinary nature of nutrition, close interaction across disciplines and optimal use of resources is necessary to better understand the relationships among diet, health and disease states/ By providing a number of Core facilities, the CNRU integrates and coordinates research activities in the field of nutrition and attempts to foster new interdisciplinary research collaboration, stimulate new research activities, improve nutrition education at multiple levels and facilitate the nutritional management of patients. The four Cores are: 1) a Laboratory Core to provide affiliate investigators with cost-efficient state-of-the-art nutritional assays and to help with new methods. development; 2) a Clinical Research Core to provide facilities and help for investigators with their clinical research, and to provide a patient registry, behavioral psychologist, and biostatistical unit; 3) An Administrative and Enrichment Core that is responsible for the day-to-day administration of the CNRU. This Core also arranges a series of seminars, retreats, and Visiting Professorships, and administers the Pilot and Feasibility and New Investigator Programs that are aimed at stimulating nutrition research by young investigators and by more established investigators new to the field of nutrition in response to evolving research interests at the University of Washington. Two new subcores have been added: A Nutrient-Gene Subcore of the Laboratory Core will provide genetically-defined mouse models for use in studies of nutrient-gene interactions; and a Body Composition and Energy Expenditure Subcore of the Clinical Research Core will provide facilities for measuring body composition and energy expenditure. Thus, the CNRU provides facilities and support for the large and varied nutrition research base of the University, thereby stimulating not only research, but also educational and clinical activities in the area of nutrition.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK035816-12
Application #
2423640
Study Section
Special Emphasis Panel (SRC (19))
Project Start
1985-09-01
Project End
2000-11-30
Budget Start
1996-12-01
Budget End
1997-11-30
Support Year
12
Fiscal Year
1997
Total Cost
Indirect Cost
Name
University of Washington
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
Subramanian, Savitha; Goodspeed, Leela; Wang, Shari et al. (2018) Deficiency of Invariant Natural Killer T Cells Does Not Protect Against Obesity but Exacerbates Atherosclerosis in Ldlr-/- Mice. Int J Mol Sci 19:
Mooney, Stephen J; Lemaitre, Rozenn N; Siscovick, David S et al. (2018) Neighborhood food environment, dietary fatty acid biomarkers, and cardiac arrest risk. Health Place 53:128-134
Han, Seung Jin; Fujimoto, Wilfred Y; Kahn, Steven E et al. (2018) Change in visceral adiposity is an independent predictor of future arterial pulse pressure. J Hypertens 36:299-305
Lemaitre, Rozenn N; Yu, Chaoyu; Hoofnagle, Andrew et al. (2018) Circulating Sphingolipids, Insulin, HOMA-IR, and HOMA-B: The Strong Heart Family Study. Diabetes 67:1663-1672
Deem, Jennifer D; Muta, Kenjiro; Ogimoto, Kayoko et al. (2018) Leptin regulation of core body temperature involves mechanisms independent of the thyroid axis. Am J Physiol Endocrinol Metab 315:E552-E564
Freeman, Sara M; Ngo, Julie; Singh, Bhavdeep et al. (2018) Effects of Chronic Oxytocin Administration and Diet Composition on Oxytocin and Vasopressin 1a Receptor Binding in the Rat Brain. Neuroscience 392:241-251
Berkseth, Kathryn E; Rubinow, Katya B; Melhorn, Susan J et al. (2018) Hypothalamic Gliosis by MRI and Visceral Fat Mass Negatively Correlate with Plasma Testosterone Concentrations in Healthy Men. Obesity (Silver Spring) 26:1898-1904
Melhorn, Susan J; Askren, Mary K; Chung, Wendy K et al. (2018) FTO genotype impacts food intake and corticolimbic activation. Am J Clin Nutr 107:145-154
Ginos, Bigina N R; Navarro, Sandi L; Schwarz, Yvonne et al. (2018) Circulating bile acids in healthy adults respond differently to a dietary pattern characterized by whole grains, legumes and fruits and vegetables compared to a diet high in refined grains and added sugars: A randomized, controlled, crossover feeding stud Metabolism 83:197-204
Shao, Dan; Villet, Outi; Zhang, Zhen et al. (2018) Glucose promotes cell growth by suppressing branched-chain amino acid degradation. Nat Commun 9:2935

Showing the most recent 10 out of 601 publications