The major objective of the Specialized Assay Core is to create greater efficiency by providingradioimmunoassays (RIAs), enzyme-linked immnosorbent assays (ELISA), immunogenetic assays, andother basic biochemical assays to support human and animal studies performed by individual DERCinvestigators at the Joslin Diabetes Center and some external users who are funded by the NIH and who donot have access to Core Facilities. Over the last 5 years, there have been several changes both in thescope of research and the number of rodent mouse models created to study various aspects of type 1 andtype 2 diabetes, obesity, their complications, and a wide variety of human studies. At Joslin more than 110rodent models have been studied over the past few years and 23 more are in various stages of beingcreated, thereby increasing a need for measurement of rodent hormones and metabolites and setting upadditional assays on a large scale. The Core allows more economic use of expensive or limited materials,provides for training of junior investigators, fosters interactions among research fellows and provides a basisfor generating collaborative studies between institutions.
Showing the most recent 10 out of 1120 publications
