The purpose of the Advanced Microscopy Core is to have sophisticated morphological techniques readilyavailable to all investigators at Joslin. The Core provides a wide range of service covering the broadcategories: performing specific morphological procedures, providing access to equipment and reagents, andgiving advice, training and interpretation. There are four main components to this core: Electron Microscopy(EM), Confocal, Histology and Laser Capture Dissection (LCM) facilities. Each has been serving Joslinresearchers by providing timely, quality morphological backup for their research needs with personalizedservice. The components run differently: the plastic embedding and electron microscope work is done by theCore Manager; the Core Histology Technician takes fixed/frozen tissue and returns slides (H&E andunstained); both the Confocal microscope and Laser Capture Microscope are used directly by the individualinvestigators with the Core training new users, providing maintenance of the microscopes, andtroubleshooting problems.
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