Abstract

The objective of the Joslin Genomics Core Facility is to provide support to Joslin and a certain number of external investigators for analysis of gene expression, by providing equipment, expertise, and services in nucleic acid analysis that would be too specialized or costly for individual laboratories to perform independently. Core services include both high-density oligonucleotide array analysis, using the Affymetrix platform, and real-time quantitative fluorescent PCR analysis. The core also provides preliminary genomic analysis, software support, and technical advice regarding experimental design and sample preparation.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK036836-23
Application #
7809551
Study Section
Special Emphasis Panel (ZDK1)
Project Start
Project End
Budget Start
2009-04-01
Budget End
2010-03-31
Support Year
23
Fiscal Year
2009
Total Cost
$191,088
Indirect Cost

  Institution

Name
Joslin Diabetes Center
Department
Type
DUNS #
071723084
City
Boston
State
MA
Country
United States
Zip Code
02215

  Publications

Viana-Huete, Vanesa; Guillén, Carlos; García, Gema et al. (2018) Male Brown Fat-Specific Double Knockout of IGFIR/IR: Atrophy, Mitochondrial Fission Failure, Impaired Thermogenesis, and Obesity. Endocrinology 159:323-340
Peterson, Claire M; Young-Hyman, Deborah; Fischer, Sarah et al. (2018) Examination of Psychosocial and Physiological Risk for Bulimic Symptoms in Youth With Type 1 Diabetes Transitioning to an Insulin Pump: A Pilot Study. J Pediatr Psychol 43:83-93
Rotroff, Daniel M; Pijut, Sonja S; Marvel, Skylar W et al. (2018) Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes. Clin Pharmacol Ther 103:712-721
Leitner, Brooks P; Weiner, Lauren S; Desir, Matthew et al. (2018) Kinetics of human brown adipose tissue activation and deactivation. Int J Obes (Lond) :
Commissariat, Persis V; Volkening, Lisa K; Guo, Zijing et al. (2018) Associations between major life events and adherence, glycemic control, and psychosocial characteristics in teens with type 1 diabetes. Pediatr Diabetes 19:85-91
Barbour, Linda A; Scifres, Christina; Valent, Amy M et al. (2018) A cautionary response to SMFM statement: pharmacological treatment of gestational diabetes. Am J Obstet Gynecol 219:367.e1-367.e7
Lammer, Jan; Karst, Sonja G; Lin, Michael M et al. (2018) Association of Microaneurysms on Adaptive Optics Scanning Laser Ophthalmoscopy With Surrounding Neuroretinal Pathology and Visual Function in Diabetes. Invest Ophthalmol Vis Sci 59:5633-5640
Gordin, Daniel; King, George L (2018) Response to Comment on Gordin et al. Differential Association of Microvascular Attributions With Cardiovascular Disease in Patients With Long Duration of Type 1 Diabetes. Diabetes Care 2018;41:815-822. Diabetes Care 41:e128
Karatepe, Kutay; Zhu, Haiyan; Zhang, Xiaoyu et al. (2018) Proteinase 3 Limits the Number of Hematopoietic Stem and Progenitor Cells in Murine Bone Marrow. Stem Cell Reports 11:1092-1105
Sustarsic, Elahu G; Ma, Tao; Lynes, Matthew D et al. (2018) Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis. Cell Metab 28:159-174.e11

Showing the most recent 10 out of 1120 publications