Abstract

This application if for 5 year funding of a University of Virginia Diabetes Endocrine Research Center. Funding is requested for Administrative, Radioimmunoassay, Tissue Culture, Biomathematics, Protein and Nucleic Acid Sequencing and Molecular Biology Cores. Funding for pilot/feasibility studies is also requested.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
3P30DK038942-03S1
Application #
3102135
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Project Start
1987-07-01
Project End
1992-11-30
Budget Start
1989-07-01
Budget End
1990-11-30
Support Year
3
Fiscal Year
1990
Total Cost
Indirect Cost

  Institution

Name
University of Virginia
Department
Type
Schools of Medicine
DUNS #
001910777
City
Charlottesville
State
VA
Country
United States
Zip Code
22904

  Publications

Earnhardt, Richard C; Veldhuis, Johannes D; Cornett, Greg et al. (2002) Pathophysiology of hyperinsulinemia following pancreas transplantation: altered pulsatile versus Basal insulin secretion and the role of specific transplant anatomy in dogs. Ann Surg 236:480-90; discussion 490-1
Lampl, M; Birch, L; Picciano, M F et al. (2001) Child factor in measurement dependability. Am J Hum Biol 13:548-57
Straume, M; Johnson, M L; Veldhuis, J D (1998) Statistically accurate estimation of hormone concentrations and associated uncertainties: methodology, validation, and applications. Clin Chem 44:116-23
Pak, Y; Hong, Y; Kim, S et al. (1998) In vivo chiro-inositol metabolism in the rat: a defect in chiro-inositol synthesis from myo-inositol and an increased incorporation of chiro-[3H]inositol into phospholipid in the Goto-Kakizaki (G.K) rat. Mol Cells 8:301-9
Friend, K; Iranmanesh, A; Login, I S et al. (1997) Pyridostigmine treatment selectively amplifies the mass of GH secreted per burst without altering GH burst frequency, half-life, basal GH secretion or the orderliness of GH release. Eur J Endocrinol 137:377-86
Reyes-Fuentes, A; Chavarria, M E; Aguilera, G et al. (1997) Deconvolution analysis of bioassayable LH secretion and half-life in men with idiopathic oligoasthenospermia. Int J Androl 20:118-25
Booth Jr, R A; Weltman, J Y; Yankov, V I et al. (1996) Mode of pulsatile follicle-stimulating hormone secretion in gonadal hormone-sufficient and -deficient women--a clinical research center study. J Clin Endocrinol Metab 81:3208-14
Veldhuis, J D (1996) Gender differences in secretory activity of the human somatotropic (growth hormone) axis. Eur J Endocrinol 134:287-95
Reyes-Fuentes, A; Chavarria, M E; Carrera, A et al. (1996) Alterations in pulsatile luteinizing hormone and follicle-stimulating hormone secretion in idiopathic oligoasthenospermic men: assessment by deconvolution analysis--a clinical research center study. J Clin Endocrinol Metab 81:524-9
Veldhuis, J D (1996) Neuroendocrine mechanisms mediating awakening of the human gonadotropic axis in puberty. Pediatr Nephrol 10:304-17

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