Abstract

THE PROPOSED SPECIFIC AIMS OF THE CELL BIOLOGY CORE ARE TO PROVIDE: 1. Space, supplies, and access to sophisticated equipment used in morphology, cell culture, and immunology 2. Specific training and supervision for utilizing specialized techniques and equipment 3. Expert consultative services in research design 4. Efficient coordinated acquisition of data and data interpretation 5. Enrichment courses in basic concepts in molecular cell biology, nutrition interaction with Gl immunology. Proposed core services provided by the NORC-H Cell Biology Core include: 1. Individual assistance, training and supervision for using specialized techniques and equipment. 2. Consultative services for morphological, immunological and tissue culture experiments. 3. Research instrumentation, technical support, and expertise in morphology, immunology and cell culture. 4. Data acquisition, analysis and interpretation. 5. Formal courses on basic concepts in molecular cell biology, and nutrition interaction with Gl immunology (at an affordable cost).

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK040561-17
Application #
8513975
Study Section
Special Emphasis Panel (ZDK1-GRB-2)
Project Start
Project End
Budget Start
2013-08-01
Budget End
2014-07-31
Support Year
17
Fiscal Year
2013
Total Cost
$154,423
Indirect Cost
$65,674

  Institution

Name
Massachusetts General Hospital
Department
Type
DUNS #
073130411
City
Boston
State
MA
Country
United States
Zip Code
02199

  Publications

Senger, Stefania; Ingano, Laura; Freire, Rachel et al. (2018) Human Fetal-Derived Enterospheres Provide Insights on Intestinal Development and a Novel Model to Study Necrotizing Enterocolitis (NEC). Cell Mol Gastroenterol Hepatol 5:549-568
Braun, Laurie R; Feldpausch, Meghan N; Czerwonka, Natalia et al. (2018) Effects of Pitavastatin on Insulin Sensitivity and Liver Fat: A Randomized Clinical Trial. J Clin Endocrinol Metab 103:4176-4186
Shivakumar, Nirupama; Dwarkanath, Pratibha; Bosch, Ronald et al. (2018) Influence of gestational weight gain on low birth weight in short-statured South Indian pregnant women. Eur J Clin Nutr 72:752-760
Gathungu, Rose M; Larrea, Pablo; Sniatynski, Matthew J et al. (2018) Optimization of Electrospray Ionization Source Parameters for Lipidomics To Reduce Misannotation of In-Source Fragments as Precursor Ions. Anal Chem 90:13523-13532
Su, Chien Wen; Chen, Chih-Yu; Li, Yali et al. (2018) Helminth infection protects against high fat diet-induced obesity via induction of alternatively activated macrophages. Sci Rep 8:4607
Cetinbas, Murat; Yu, Shen; Sadreyev, Ruslan I (2018) Whole Genome Next-Generation Sequencing Mutation Identification in Pseudomonas aeruginosa. Curr Protoc Mol Biol 124:e69
Singhal, Vibha; Tulsiani, Shreya; Campoverde, Karen Joanie et al. (2018) Impaired bone strength estimates at the distal tibia and its determinants in adolescents with anorexia nervosa. Bone 106:61-68
Ji, Fei; Sadreyev, Ruslan I (2018) RNA-seq: Basic Bioinformatics Analysis. Curr Protoc Mol Biol 124:e68
Holsen, L M; Davidson, P; Cerit, H et al. (2018) Neural predictors of 12-month weight loss outcomes following bariatric surgery. Int J Obes (Lond) 42:785-793
Kyle, Theodore K; Stanford, Fatima Cody; Nadglowski, Joseph F (2018) Addressing Weight Stigma and Opening Doors for a Patient-Centered Approach to Childhood Obesity. Obesity (Silver Spring) 26:457-458

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