Abstract

CURE has always strived to be on the forefront of gastrointestinal research, and it has been uniquely able to translate basic cellular advances into human studies in patients with gastrointestinal diseases. The importance and significance of Gl disorders is highlighted by their national impact on quality of life and demand for health care services. In this context, the Human Studies Core is part of the CURE: Digestive Disease Research Core Center (CURE: DDRCC) since it was created in 1989. The mission of the Human Studies Core of the CURE: Digestive Disease Research Core Center (CURE: DDRCC) is to provide shared resources, personnel, services, education, and consultation to CURE: DDRCC investigators, trainees, and their collaborators for the study of patients with selected digestive disorders. The primary objective of this Core is to facilitate collaboration, education about, and performance of Gl clinical, human physiological studies, translational, and health outcomes studies in selected digestive disorders.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK041301-23
Application #
8374972
Study Section
Special Emphasis Panel (ZDK1-GRB-8)
Project Start
Project End
Budget Start
2011-12-01
Budget End
2012-11-30
Support Year
23
Fiscal Year
2012
Total Cost
$114,649
Indirect Cost
$23,658

  Institution

Name
University of California Los Angeles
Department
Type
DUNS #
092530369
City
Los Angeles
State
CA
Country
United States
Zip Code
90095

  Publications

Dong, Tien; Pisegna, Joseph (2018) Passing the ""Acid Test"": Do Proton Pump Inhibitors Affect the Composition of the Microbiome? Dig Dis Sci :
Park, S H; Naliboff, B D; Shih, W et al. (2018) Resilience is decreased in irritable bowel syndrome and associated with symptoms and cortisol response. Neurogastroenterol Motil 30:
Jacobs, Jonathan P; Dong, Tien S; Agopian, Vatche et al. (2018) Microbiome and bile acid profiles in duodenal aspirates from patients with liver cirrhosis: The Microbiome, Microbial Markers and Liver Disease Study. Hepatol Res :
Basheer, Wassim A; Fu, Ying; Shimura, Daisuke et al. (2018) Stress response protein GJA1-20k promotes mitochondrial biogenesis, metabolic quiescence, and cardioprotection against ischemia/reperfusion injury. JCI Insight 3:
Lin, De-Chen; Dinh, Huy Q; Xie, Jian-Jun et al. (2018) Identification of distinct mutational patterns and new driver genes in oesophageal squamous cell carcinomas and adenocarcinomas. Gut 67:1769-1779
Sala-Rabanal, Monica; Ghezzi, Chiara; Hirayama, Bruce A et al. (2018) Intestinal absorption of glucose in mice as determined by positron emission tomography. J Physiol 596:2473-2489
Bhattarai, Yogesh; Williams, Brianna B; Battaglioli, Eric J et al. (2018) Gut Microbiota-Produced Tryptamine Activates an Epithelial G-Protein-Coupled Receptor to Increase Colonic Secretion. Cell Host Microbe 23:775-785.e5
Tsang, Eric J; Wu, Benjamin; Zuk, Patricia (2018) MAPK signaling has stage-dependent osteogenic effects on human adipose-derived stem cells in vitro. Connect Tissue Res 59:129-146
May, Folasade P; Yu, Christine; Kaunitz, Jonathan (2018) High quality of cancer care in the Department of Veterans Affairs (VA). Am J Cancer Res 8:761-762
Osadchiy, Vadim; Labus, Jennifer S; Gupta, Arpana et al. (2018) Correlation of tryptophan metabolites with connectivity of extended central reward network in healthy subjects. PLoS One 13:e0201772

Showing the most recent 10 out of 1097 publications