Abstract

application) The purpose of the Biochemistry and Biophysics Core Laboratory is to provide experimental facilities and expertise in biochemical and biophysical techniques. This includes: isolation of plasma membranes and intracellular membranes, analysis of neutral lipid and phospholipid composition of these membranes, analysis of phosphatidylinositol metabolism in cells and membranes, assess the static and dynamic rotational mobilities, measurement of excited state in membrane preparations, measure intracellular Ca and pH in suspensions, measure IP3 levels, DAG mass and glycosphingolipids, Western blotting and immunohistochemical techniques (signal transduction elements). In addition the Core will train users in these methodologies, surveillance and quality control of techniques. The services are said to be provided in a cost-effective manner through core resources, given the expense of the equipment needed to perform these sophisticated analyses.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
2P30DK042086-11
Application #
6450019
Study Section
Project Start
1990-01-01
Project End
2005-11-30
Budget Start
Budget End
Support Year
11
Fiscal Year
2001
Total Cost
Indirect Cost

  Institution

Name
University of Chicago
Department
Type
DUNS #
225410919
City
Chicago
State
IL
Country
United States
Zip Code
60637

  Publications

Feagan, Brian G; Schwartz, David; Danese, Silvio et al. (2018) Efficacy of Vedolizumab in Fistulising Crohn's Disease: Exploratory Analyses of Data from GEMINI 2. J Crohns Colitis 12:621-626
Delmont, Tom O; Eren, A Murat (2018) Linking pangenomes and metagenomes: the Prochlorococcus metapangenome. PeerJ 6:e4320
Salas Garcia, Mariana C; Yee, Alyson L; Gilbert, Jack A et al. (2018) Dysbiosis in Children Born by Caesarean Section. Ann Nutr Metab 73 Suppl 3:24-32
Cardona, Cesar; Lax, Simon; Larsen, Peter et al. (2018) Environmental Sources of Bacteria Differentially Influence Host-Associated Microbial Dynamics. mSystems 3:
Micic, Dejan; Hirsch, Ayal; Setia, Namrata et al. (2018) Enteric infections complicating ulcerative colitis. Intest Res 16:489-493
He, Lei; Liu, Tianjing; Shi, Yongyan et al. (2018) Gut Epithelial Vitamin D Receptor Regulates Microbiota-Dependent Mucosal Inflammation by Suppressing Intestinal Epithelial Cell Apoptosis. Endocrinology 159:967-979
Kane, Melissa; Deiss, Felicity; Chervonsky, Alexander et al. (2018) A Single Locus Controls Interferon Gamma-Independent Antiretroviral Neutralizing Antibody Responses. J Virol 92:
Wang, C-Z; Huang, W-H; Zhang, C-F et al. (2018) Role of intestinal microbiome in American ginseng-mediated colon cancer prevention in high fat diet-fed AOM/DSS mice [corrected]. Clin Transl Oncol 20:302-312
Wali, Ramesh K; Bianchi, Laura; Kupfer, Sonia et al. (2018) Prevention of colonic neoplasia with polyethylene glycol: A short term randomized placebo-controlled double-blinded trial. PLoS One 13:e0193544
Gaines, S; Shao, C; Hyman, N et al. (2018) Gut microbiome influences on anastomotic leak and recurrence rates following colorectal cancer surgery. Br J Surg 105:e131-e141

Showing the most recent 10 out of 697 publications