The Administrative Core is led by Center Director Ramnik Xavier and Associate Directors Atul Bhan, Cornelis Terhorst, and Mark Daly. The activities of the Center?s Administrative Core serve to support the Center?s goals of promoting interactions among scientists exploring diverse fields which share relevance to IBD, attracting investigators to the study of IBD, and providing an environment and mechanism to foster development of young investigators focused on IBD. We believe all these goals are achieved through the scientific and material resources provided via the organizational framework of this Center.
The specific aims of the Administrative Core are to (1) promote scientific interactions among members; (2) coordinate the Enrichment Program offerings; (3) facilitate and provide oversight of the Pilot and Feasibility Program; (4) identify, help develop, and promote tools, technologies, and collaborations; (5) assist the director in making general, administrative, and scientific decisions concerning the overall direction of the CSIBD and plans to implement changes and/or new initiatives within the Center and provide ongoing assessment of productivity, effectiveness, and appropriateness of biomedical core activities; and (6) facilitate interactions with other DDRCCs, the NIDDK and other appropriate individuals, groups, and/or organizations and maintain communication of activities through venues such as the CSIBD website. The Administrative Core also manages the collaborative program between the CSIBD and the Broad Institute, which has been expanded in the current funding period to include ?Core Enhancement? grants that enable access to Broad Institute-based platforms. More details on this program are provided in the Administrative Core Research Strategy.

National Institute of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Center Core Grants (P30)
Project #
Application #
Study Section
Special Emphasis Panel (ZDK1)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Massachusetts General Hospital
United States
Zip Code
Zhang, Sidi; Samocha, Kaitlin E; Rivas, Manuel A et al. (2018) Base-specific mutational intolerance near splice sites clarifies the role of nonessential splice nucleotides. Genome Res 28:968-974
Beaulieu, Dawn B; Ananthakrishnan, Ashwin N; Martin, Christopher et al. (2018) Use of Biologic Therapy by Pregnant Women With Inflammatory Bowel Disease Does Not Affect Infant Response to Vaccines. Clin Gastroenterol Hepatol 16:99-105
Hui, Ken Y; Fernandez-Hernandez, Heriberto; Hu, Jianzhong et al. (2018) Functional variants in the LRRK2 gene confer shared effects on risk for Crohn's disease and Parkinson's disease. Sci Transl Med 10:
Chong, Dawn Q; Banbury, Barbara L; Phipps, Amanda I et al. (2018) Association of family history and survival in patients with colorectal cancer: a pooled analysis of eight epidemiologic studies. Cancer Med 7:2192-2199
Johns, Nathan I; Gomes, Antonio L C; Yim, Sung Sun et al. (2018) Metagenomic mining of regulatory elements enables programmable species-selective gene expression. Nat Methods 15:323-329
Garber, John J; Mallick, Emily M; Scanlon, Karen M et al. (2018) Attaching-and-Effacing Pathogens Exploit Junction Regulatory Activities of N-WASP and SNX9 to Disrupt the Intestinal Barrier. Cell Mol Gastroenterol Hepatol 5:273-288
Yu, Sheng; Ma, Yumeng; Gronsbell, Jessica et al. (2018) Enabling phenotypic big data with PheNorm. J Am Med Inform Assoc 25:54-60
Bakker, Olivier B; Aguirre-Gamboa, Raul; Sanna, Serena et al. (2018) Integration of multi-omics data and deep phenotyping enables prediction of cytokine responses. Nat Immunol 19:776-786
Cox, Kimberly H; Oliveira, Luciana M B; Plummer, Lacey et al. (2018) Modeling mutant/wild-type interactions to ascertain pathogenicity of PROKR2 missense variants in patients with isolated GnRH deficiency. Hum Mol Genet 27:338-350
Ingram, Jessica R; Blomberg, Olga S; Rashidian, Mohammad et al. (2018) Anti-CTLA-4 therapy requires an Fc domain for efficacy. Proc Natl Acad Sci U S A 115:3912-3917

Showing the most recent 10 out of 1166 publications