Abstract

The objectives of this core are the following. 1. Provide statistical and epidemiologic support to ongoing or planned obesity studies in the Boston area, which will, in turn, expand the nucleus of expertise and familiarity with design and analysis issues unique to obesity research. 2. Continue to support the development and maintenance of data sets amendable to secondary epidemiologic analyses regarding obesity and nutrition issues as well as to develop and refine measures of obesity. 3. Interface epidemiology, basic sciences, and clinical medicine so that hypotheses generated by these areas can be tested in ongoing epidemiologic studies. 4. Train young investigators in epidemiologic and statistical techniques used for the study of obesity in populations. 5. Disseminate methods/approaches to data analysis to a broad audience, as Core members gain experience in applying and refining quantitative methods. 6. Help identify groups at high and low risk of the development of obesity, and population characteristics for obesity clinical trials.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK046200-10
Application #
6500764
Study Section
Project Start
2001-09-30
Project End
2003-03-31
Budget Start
Budget End
Support Year
10
Fiscal Year
2001
Total Cost
Indirect Cost

  Institution

Name
Boston Medical Center
Department
Type
DUNS #
005492160
City
Boston
State
MA
Country
United States
Zip Code
02118

  Publications

Killion, Elizabeth A; Reeves, Andrew R; El Azzouny, Mahmoud A et al. (2018) A role for long-chain acyl-CoA synthetase-4 (ACSL4) in diet-induced phospholipid remodeling and obesity-associated adipocyte dysfunction. Mol Metab 9:43-56
Leitner, Brooks P; Weiner, Lauren S; Desir, Matthew et al. (2018) Kinetics of human brown adipose tissue activation and deactivation. Int J Obes (Lond) :
Gaskins, Audrey J; Rich-Edwards, Janet W; Williams, Paige L et al. (2018) Pre-pregnancy caffeine and caffeinated beverage intake and risk of spontaneous abortion. Eur J Nutr 57:107-117
Hansen, S; Halldorsson, T I; Olsen, S F et al. (2018) Birth by cesarean section in relation to adult offspring overweight and biomarkers of cardiometabolic risk. Int J Obes (Lond) 42:15-19
Maldonado-Cárceles, Ana B; Mínguez-Alarcón, Lidia; Mendiola, Jaime et al. (2018) Meat intake in relation to semen quality and reproductive hormone levels among young men in Spain. Br J Nutr :1-10
Han, Liyuan; Duan, Donghui; Zhang, Shuang et al. (2018) Effects of the interaction between glycated haemoglobin genetic risk score and postpartum weight reduction on glycaemic changes: A gene-weight interaction analysis. Diabetes Obes Metab 20:2733-2739
Jager, Mike; Lee, Mi-Jeong; Li, Chendi et al. (2018) Aortic carboxypeptidase-like protein enhances adipose tissue stromal progenitor differentiation into myofibroblasts and is upregulated in fibrotic white adipose tissue. PLoS One 13:e0197777
Cardamone, Maria Dafne; Tanasa, Bogdan; Cederquist, Carly T et al. (2018) Mitochondrial Retrograde Signaling in Mammals Is Mediated by the Transcriptional Cofactor GPS2 via Direct Mitochondria-to-Nucleus Translocation. Mol Cell 69:757-772.e7
Martin Carli, Jayne F; LeDuc, Charles A; Zhang, Yiying et al. (2018) FTO mediates cell-autonomous effects on adipogenesis and adipocyte lipid content by regulating gene expression via 6mA DNA modifications. J Lipid Res 59:1446-1460
Buendia, Justin R; Li, Yanping; Hu, Frank B et al. (2018) Regular Yogurt Intake and Risk of Cardiovascular Disease Among Hypertensive Adults. Am J Hypertens 31:557-565

Showing the most recent 10 out of 876 publications