? This application represents the third competing renewal of the Boston Obesity Nutrition Research Center. The Boston Obesity Nutrition Research Center represents a collaboration of three major universities representing six major organizations, all located within a 1.5 mile radius of one another. The Boston Obesity Center includes Tufts-New England Medical Center, Beth Israel Deaconess Medical Center, Massachusetts General Hospital, Harvard School of Public Health, Boston Medical Center and the Human Nutrition Research Center on Aging. These institutions represent Tufts University, Harvard University and Boston University, respectively The research base has increased from 97 to 163 and includes members from these institutions as well as several new ones, including the University of Massachusetts Boston and the University of Massachusetts Medical School (Worcester) and it affiliated University Center for Excellence in Developmental Disabilities at the Eunice Kennedy Shriver Center in Waltham. ? The Boston Obesity Nutrition Research Center consists of four Core laboratories. These include an Adipocyte Core directed by Dr. James Kirkland, a Clinical and Community Research Core directed by Dr. Aviva Must, an Epidemiology and Genetics Core directed by Dr. Frank Hu and a Transgenic Core directed by Dr. Bradford Lowell. The Obesity Center offers many opportunities for education and training in obesity research to fellows on training grants held by Obesity Center investigators in each of the collaborating institutions. ? The investigators represented in this application are Principal Investigators on 171 funded NIH grants, approximately 143 of which are directed at the study of obesity, energy metabolism or other nutritional diseases. In the past five years, the Boston Obesity Center investigators have published 283 papers with Center support. Currently, fifteen percent of the Obesity Center's budget provides support for pilot and feasibility studies. Pilot and feasibility award recipients have published 640 papers and received a total of 41 grants from NIH or other funding agencies based on the data obtained from their Center-funded and subsequent research in obesity and nutrition. ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
2P30DK046200-16
Application #
7456184
Study Section
Special Emphasis Panel (ZDK1-GRB-6 (J1))
Program Officer
Miles, Carolyn
Project Start
1997-09-30
Project End
2013-03-31
Budget Start
2008-06-01
Budget End
2009-03-31
Support Year
16
Fiscal Year
2008
Total Cost
$1,119,245
Indirect Cost
Name
Boston Medical Center
Department
Type
DUNS #
005492160
City
Boston
State
MA
Country
United States
Zip Code
02118
Stockman, Mary-Catherine; Thomas, Dylan; Burke, Jacquelyn et al. (2018) Intermittent Fasting: Is the Wait Worth the Weight? Curr Obes Rep 7:172-185
Roh, Hyun Cheol; Tsai, Linus T Y; Shao, Mengle et al. (2018) Warming Induces Significant Reprogramming of Beige, but Not Brown, Adipocyte Cellular Identity. Cell Metab 27:1121-1137.e5
Bray, George A; Heisel, William E; Afshin, Ashkan et al. (2018) The Science of Obesity Management: An Endocrine Society Scientific Statement. Endocr Rev 39:79-132
Hou, Xiaoli; Zhang, Yongzhao; Li, Wei et al. (2018) CDK6 inhibits white to beige fat transition by suppressing RUNX1. Nat Commun 9:1023
Mínguez-Alarcón, Lidia; Afeiche, Myriam C; Williams, Paige L et al. (2018) Hair mercury (Hg) levels, fish consumption and semen parameters among men attending a fertility center. Int J Hyg Environ Health 221:174-182
Nassan, Feiby L; Chiu, Yu-Han; Vanegas, Jose C et al. (2018) Intake of protein-rich foods in relation to outcomes of infertility treatment with assisted reproductive technologies. Am J Clin Nutr 108:1104-1112
Arvizu, Mariel; Afeiche, Myriam C; Hansen, Susanne et al. (2018) Fat intake during pregnancy and risk of preeclampsia: a prospective cohort study in Denmark. Eur J Clin Nutr :
Harris, H R; Eke, A C; Chavarro, J E et al. (2018) Fruit and vegetable consumption and risk of endometriosis. Hum Reprod 33:715-727
Kong, Xingxing; Yao, Ting; Zhou, Peng et al. (2018) Brown Adipose Tissue Controls Skeletal Muscle Function via the Secretion of Myostatin. Cell Metab 28:631-643.e3
Nisa, Hoirun; Qi, Kevin H T; Leng, Junhong et al. (2018) The Circadian Rhythm-Related MTNR1B Genotype, Gestational Weight Gain, and Postpartum Glycemic Changes. J Clin Endocrinol Metab 103:2284-2290

Showing the most recent 10 out of 876 publications