Abstract

application) The primary function of the Biochemistry Section is to provide reliable assays for the measures used in obesity-related research at the University of Pittsburgh, including amino acids, insulin, lipids, lipoproteins, and vitamins. The primary function of the Genetics Section is to provide genotype assays for genes of interest to Obesity/Nutrition research at the University. These include genes involved in lipoprotein/lipid metabolism, obesity, bone mineral metabolism, and glucose metabolism. Both the Biochemistry and Genetics components of the core will provide consultation to investigators regarding the selection of assays to include in specific research studies, on appropriate procedures for preparing samples, and on the availability of other assays on the University of Pittsburgh campus. The Biochemistry and Genetics Core provides long-term storage for blood and cell samples from all patients seen in the Metabolism Core, develops new biochemical and genotype assays to meet the needs of ONRC investigators and to stimulate new research directions, provides training opportunities for students, postdoctoral fellows, and staff members from other laboratories, and aids in the preparation of grants and manuscripts.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
3P30DK046204-10S1
Application #
6666373
Study Section
Project Start
2001-09-30
Project End
2003-03-31
Budget Start
Budget End
Support Year
10
Fiscal Year
2002
Total Cost
$103,677
Indirect Cost

  Institution

Name
University of Pittsburgh
Department
Type
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213

  Publications

Coen, Paul M; Carnero, Elvis A; Goodpaster, Bret H (2018) Exercise and Bariatric Surgery: An Effective Therapeutic Strategy. Exerc Sport Sci Rev 46:262-270
Hayden, Kathleen M; Baker, Laura D; Bray, George et al. (2018) Long-term impact of intensive lifestyle intervention on cognitive function assessed with the National Institutes of Health Toolbox: The Look AHEAD study. Alzheimers Dement (Amst) 10:41-48
Chao, Ariana M; Wadden, Thomas A; Gorin, Amy A et al. (2017) Binge Eating and Weight Loss Outcomes in Individuals with Type 2 Diabetes: 4-Year Results from the Look AHEAD Study. Obesity (Silver Spring) 25:1830-1837
Gallagher, Dympna; Kelley, David E; Thornton, John et al. (2017) Changes in skeletal muscle and organ size after a weight-loss intervention in overweight and obese type 2 diabetic patients. Am J Clin Nutr 105:78-84
Unick, Jessica L; Gaussoin, Sarah A; Hill, James O et al. (2017) Objectively Assessed Physical Activity and Weight Loss Maintenance among Individuals Enrolled in a Lifestyle Intervention. Obesity (Silver Spring) 25:1903-1909
Nunez Lopez, Y O; Coen, P M; Goodpaster, B H et al. (2017) Gastric bypass surgery with exercise alters plasma microRNAs that predict improvements in cardiometabolic risk. Int J Obes (Lond) 41:1121-1130
Johnson, Karen C; Bray, George A; Cheskin, Lawrence J et al. (2017) The Effect of Intentional Weight Loss on Fracture Risk in Persons With Diabetes: Results From the Look AHEAD Randomized Clinical Trial. J Bone Miner Res 32:2278-2287
Beavers, Kristen M; Leng, Iris; Rapp, Stephen R et al. (2017) Effects of Longitudinal Glucose Exposure on Cognitive and Physical Function: Results from the Action for Health in Diabetes Movement and Memory Study. J Am Geriatr Soc 65:137-145
Marquez, Becky; Anderson, Andrea; Wing, Rena R et al. (2016) The relationship of social support with treatment adherence and weight loss in Latinos with type 2 diabetes. Obesity (Silver Spring) 24:568-75
Belalcazar, L Maria; Papandonatos, George D; Erar, Bahar et al. (2016) Lifestyle Intervention for Weight Loss and Cardiometabolic Changes in the Setting of Glucokinase Regulatory Protein Inhibition: Glucokinase Regulatory Protein-Leu446Pro Variant in Look AHEAD. Circ Cardiovasc Genet 9:71-8

Showing the most recent 10 out of 148 publications