Project Start
2002-01-01
Project End
2002-12-31
Budget Start
Budget End
Support Year
9
Fiscal Year
2002
Total Cost
Indirect Cost
Name
University of Washington
Department
Type
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
Murnane, R; Zhang, X B; Hukkanen, R R et al. (2011) Myelodysplasia in 2 pig-tailed macaques (Macaca nemestrina) associated with retroviral vector-mediated insertional mutagenesis and overexpression of HOXB4. Vet Pathol 48:999-1001
Metzger, Michael J; McConnell-Smith, Audrey; Stoddard, Barry L et al. (2011) Single-strand nicks induce homologous recombination with less toxicity than double-strand breaks using an AAV vector template. Nucleic Acids Res 39:926-35
Miller, A D; Metzger, M J (2011) APOBEC3-mediated hypermutation of retroviral vectors produced from some retrovirus packaging cell lines. Gene Ther 18:528-30
Halbert, C L; Metzger, M J; Lam, S-L et al. (2011) Capsid-expressing DNA in AAV vectors and its elimination by use of an oversize capsid gene for vector production. Gene Ther 18:411-7
Kiem, Hans-Peter; Ironside, Christina; Beard, Brian C et al. (2010) A retroviral vector common integration site between leupaxin and zinc finger protein 91 (ZFP91) observed in baboon hematopoietic repopulating cells. Exp Hematol 38:819-22, 822.e1-3
Trobridge, Grant D; Wu, Robert A; Hansen, Michael et al. (2010) Cocal-pseudotyped lentiviral vectors resist inactivation by human serum and efficiently transduce primate hematopoietic repopulating cells. Mol Ther 18:725-33
Becker, P S; Taylor, J A; Trobridge, G D et al. (2010) Preclinical correction of human Fanconi anemia complementation group A bone marrow cells using a safety-modified lentiviral vector. Gene Ther 17:1244-52
Doty, Raymond T; Sabo, Kathleen M; Chen, Jing et al. (2010) An all-feline retroviral packaging system for transduction of human cells. Hum Gene Ther 21:1019-27
Enssle, Joerg; Trobridge, Grant D; Keyser, Kirsten A et al. (2010) Stable marking and transgene expression without progression to monoclonality in canine long-term hematopoietic repopulating cells transduced with lentiviral vectors. Hum Gene Ther 21:397-403
Halbert, Christine L; Madtes, David K; Vaughan, Andrew E et al. (2010) Expression of human alpha1-antitrypsin in mice and dogs following AAV6 vector-mediated gene transfer to the lungs. Mol Ther 18:1165-72

Showing the most recent 10 out of 176 publications