Abstract

The overall theme of the Metabolic Core lab is to support investigation of insulin resistance, obesity, and fetal growth from a cellular/molecular perspective. The Metabolic core also provides consultation and analysis of insulin signaling and performance hormone assays tailored to the investigators needs. This core provides a bridge between whole animal/human investigation and an array of molecular and cellular assays of key metabolic targets underlying insulin resistance, weight gain, and maternal-fetal metabolism.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK048520-12
Application #
7311540
Study Section
Special Emphasis Panel (ZDK1)
Project Start
Project End
Budget Start
2006-08-01
Budget End
2007-07-31
Support Year
12
Fiscal Year
2006
Total Cost
$169,400
Indirect Cost

  Institution

Name
University of Colorado Denver
Department
Type
DUNS #
041096314
City
Aurora
State
CO
Country
United States
Zip Code
80045

  Publications

Jensen, Thomas; Abdelmalek, Manal F; Sullivan, Shelby et al. (2018) Fructose and sugar: A major mediator of non-alcoholic fatty liver disease. J Hepatol 68:1063-1075
Lanaspa, Miguel A; Kuwabara, Masanari; Andres-Hernando, Ana et al. (2018) High salt intake causes leptin resistance and obesity in mice by stimulating endogenous fructose production and metabolism. Proc Natl Acad Sci U S A 115:3138-3143
Bergman, Bryan C; Perreault, Leigh; Strauss, Allison et al. (2018) Intramuscular triglyceride synthesis: importance in muscle lipid partitioning in humans. Am J Physiol Endocrinol Metab 314:E152-E164
Rynders, Corey A; Schmidt, Stacy L; Bergouignan, Audrey et al. (2018) Effects of short-term sex steroid suppression on dietary fat storage patterns in healthy males. Physiol Rep 6:
Friedman, Jacob E; Dobrinskikh, Evgenia; Alfonso-Garcia, Alba et al. (2018) Pyrroloquinoline quinone prevents developmental programming of microbial dysbiosis and macrophage polarization to attenuate liver fibrosis in offspring of obese mice. Hepatol Commun 2:313-328
Saxon, David R; Rasouli, Neda; Eckel, Robert H (2018) Pharmacological Prevention of Cardiovascular Outcomes in Diabetes Mellitus: Established and Emerging Agents. Drugs 78:203-214
Brunette, Amanda M; Holm, Kristen E; Wamboldt, Frederick S et al. (2018) Subjective cognitive complaints and neuropsychological performance in former smokers with and without chronic obstructive pulmonary disease. J Clin Exp Neuropsychol 40:411-422
Nowak, Kristen L; Rossman, Matthew J; Chonchol, Michel et al. (2018) Strategies for Achieving Healthy Vascular Aging. Hypertension 71:389-402
Perreault, Leigh; Newsom, Sean A; Strauss, Allison et al. (2018) Intracellular localization of diacylglycerols and sphingolipids influences insulin sensitivity and mitochondrial function in human skeletal muscle. JCI Insight 3:
Peters, John C; Marker, Ryan; Pan, Zhaoxing et al. (2018) The Influence of Adding Spices to Reduced Sugar Foods on Overall Liking. J Food Sci 83:814-821

Showing the most recent 10 out of 756 publications