Abstract

The overall theme of the Metabolic Core lab is to support investigation of insulin resistance, obesity, and fetal growth from a cellular/molecular perspective. The Metabolic core also provides consultation and analysis of insulin signaling and performance hormone assays tailored to the investigators needs. This core provides a bridge between whole animal/human investigation and an array of molecular and cellular assays of key metabolic targets underlying insulin resistance, weight gain, and maternal-fetal metabolism.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK048520-15
Application #
7910648
Study Section
Special Emphasis Panel (ZDK1)
Project Start
Project End
Budget Start
2009-08-01
Budget End
2010-07-31
Support Year
15
Fiscal Year
2009
Total Cost
$363,537
Indirect Cost

  Institution

Name
University of Colorado Denver
Department
Type
DUNS #
041096314
City
Aurora
State
CO
Country
United States
Zip Code
80045

  Publications

Lee, Dustin M; Battson, Micah L; Jarrell, Dillon K et al. (2018) SGLT2 inhibition via dapagliflozin improves generalized vascular dysfunction and alters the gut microbiota in type 2 diabetic mice. Cardiovasc Diabetol 17:62
Alexeev, Erica E; Lanis, Jordi M; Kao, Daniel J et al. (2018) Microbiota-Derived Indole Metabolites Promote Human and Murine Intestinal Homeostasis through Regulation of Interleukin-10 Receptor. Am J Pathol 188:1183-1194
Beli, Eleni; Yan, Yuanqing; Moldovan, Leni et al. (2018) Restructuring of the Gut Microbiome by Intermittent Fasting Prevents Retinopathy and Prolongs Survival in db/db Mice. Diabetes 67:1867-1879
Mintz, Michael; Khair, Shanawaj; Grewal, Suman et al. (2018) Longitudinal microbiome analysis of single donor fecal microbiota transplantation in patients with recurrent Clostridium difficile infection and/or ulcerative colitis. PLoS One 13:e0190997
Keller, A C; Knaub, L A; Scalzo, R L et al. (2018) Sepiapterin Improves Vascular Reactivity and Insulin-Stimulated Glucose in Wistar Rats. Oxid Med Cell Longev 2018:7363485
Creasy, Seth A; Rynders, Corey A; Bergouignan, Audrey et al. (2018) Free-Living Responses in Energy Balance to Short-Term Overfeeding in Adults Differing in Propensity for Obesity. Obesity (Silver Spring) 26:696-702
Hildreth, Kerry L; Ozemek, Cemal; Kohrt, Wendy M et al. (2018) Vascular dysfunction across the stages of the menopausal transition is associated with menopausal symptoms and quality of life. Menopause 25:1011-1019
Beune, Irene M; Bloomfield, Frank H; Ganzevoort, Wessel et al. (2018) Consensus Based Definition of Growth Restriction in the Newborn. J Pediatr 196:71-76.e1
Rynders, Corey A; Schmidt, Stacy L; Bergouignan, Audrey et al. (2018) Effects of short-term sex steroid suppression on dietary fat storage patterns in healthy males. Physiol Rep 6:
Jensen, Thomas; Abdelmalek, Manal F; Sullivan, Shelby et al. (2018) Fructose and sugar: A major mediator of non-alcoholic fatty liver disease. J Hepatol 68:1063-1075

Showing the most recent 10 out of 756 publications