The overall goals of the Disordered Eating Behavior Core are to provide assistance to participating MNOCinvestigators in the assessment of disordered eating and other psychopathology, and the development ofinterventions for such disordered eating. These services are applicable both to the study of obesity and to thestudy of 'classic' forms of disordered eating including clinically diagnosable eating disorders. Servicesprovided through this Core are organized in the following sections:1. Clinical Assessment: The Core provides consultation regarding assessment of disordered eating andother behaviors; training and ongoing quality improvement/quality assurance for trained assessors; andthe conduct of structured assessments.2. Treatment Development: The Core provides consultation to investigators regarding the development ofmanual-based treatments for obesity and disordered eating, and is actively engaged in suchdevelopment efforts. In addition, the Core provides certain structured therapeutic interventions (suchas Cognitive Behavioral Therapy) for ongoing projects.3. Access to Clinical Populations: The Core provides access to populations of potential subjects witheating disorders diagnoses; subjects with other psychopathology; non-affected comparison groups;obese samples; and archival data sets.4. Technology-Based Methods of Data Accumulation: The Core provides access to several emergingtechnologies for the highly accurate on cost-effective accumulation of research data, such asecological momentary assessment, and data scanning/online data entry.5. Cost Effectiveness Analysis: The Core provides consultation regarding the collection of costeffectiveness data in clinical trials. Services provided by this Core are highly labor-intensive, requiringindividuals with advanced training plus expensive, specialized experience in behavioral assessments,treatments or both. It would be impractical, expensive and often impossible for investigators to recreatethis capacity in their own group.

National Institute of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Center Core Grants (P30)
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Special Emphasis Panel (ZDK1-GRB-W (J1))
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University of Minnesota Twin Cities
United States
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Roelfsema, Ferdinand; Yang, Rebecca J; Takahashi, Paul Y et al. (2018) Effects of Toremifene, a Selective Estrogen Receptor Modulator, on Spontaneous and Stimulated GH Secretion, IGF-I, and IGF-Binding Proteins in Healthy Elderly Subjects. J Endocr Soc 2:154-165
Egbert, Amy Heard; Wilfley, Denise E; Eddy, Kamryn T et al. (2018) Attention-Deficit/Hyperactivity Disorder Symptoms Are Associated with Overeating with and without Loss of Control in Youth with Overweight/Obesity. Child Obes 14:50-57
Qiu, Xiaoxue; Guo, Hong; Yang, Junshu et al. (2018) Down-regulation of guanylate binding protein 1 causes mitochondrial dysfunction and cellular senescence in macrophages. Sci Rep 8:1679
Mason, Tyler B; Smith, Kathryn E; Crosby, Ross D et al. (2018) Does the eating disorder examination questionnaire global subscale adequately predict eating disorder psychopathology in the daily life of obese adults? Eat Weight Disord 23:521-526
Levis, Brooke; Benedetti, Andrea; Riehm, Kira E et al. (2018) Probability of major depression diagnostic classification using semi-structured versus fully structured diagnostic interviews. Br J Psychiatry 212:377-385
Goldschmidt, Andrea B; Crosby, Ross D; Cao, Li et al. (2018) A preliminary study of momentary, naturalistic indicators of binge-eating episodes in adults with obesity. Int J Eat Disord 51:87-91
Roelfsema, Ferdinand; Yang, Rebecca J; Veldhuis, Johannes D (2018) Estradiol Does Not Influence Lipid Measures and Inflammatory Markers in Testosterone-Clamped Healthy Men. J Endocr Soc 2:882-892
Ikramuddin, Sayeed; Korner, Judith; Lee, Wei-Jei et al. (2018) Lifestyle Intervention and Medical Management With vs Without Roux-en-Y Gastric Bypass and Control of Hemoglobin A1c, LDL Cholesterol, and Systolic Blood Pressure at 5 Years in the Diabetes Surgery Study. JAMA 319:266-278
Espinosa De Ycaza, A E; Donegan, D; Jensen, M D (2018) Long-term metabolic risk for the metabolically healthy overweight/obese phenotype. Int J Obes (Lond) 42:302-309
Jahansouz, C; Xu, H; Hertzel, A V et al. (2018) Partitioning of adipose lipid metabolism by altered expression and function of PPAR isoforms after bariatric surgery. Int J Obes (Lond) 42:139-146

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