The public health significance of disordered eating behavior is great. These are relatively common disorders, affecting primarily women;overall at least 2.5% of the population is affected.(1,2) Rates of less severe but still disordered eating among teens and college students are higher still. Population-based studies show that 7% of adolescent females and 3% of adolescent boys report using unhealthy weight control behaviors, such as purging or skipping meals, to manage their weight."""""""" The economic and social burdens of eating disorders are substantial.(8,9) Medical complications are extremely common and the rate of mortality is very high. In fact, well-designed studies have found a mortality rate in anorexia nervosa of over one half percent per year(10,11) and recent evidence documents elevated mortality in other eating disorders as well.(12) Moreover, disordered eating may be important to our understanding of the causes, prevention, and treatment of obesity. For example, patterns of binge eating and night eating in obese individuals have been recognized for over 50 years(13) The phenomenon of binge eating has been a topic of increased interest and controversy over the last 15-20 years. In summary, disordered eating has a high prevalence rate, significant medical and psychosocial co-morbidities, and important implications for treating and preventing obesity. For these reasons, a Disordered Eating Behavior Core is a valuable component of the center.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK050456-19
Application #
8640140
Study Section
Special Emphasis Panel (ZDK1)
Project Start
Project End
Budget Start
2014-04-01
Budget End
2015-03-31
Support Year
19
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Type
DUNS #
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
McGee-Lawrence, Meghan E; Pierce, Jessica L; Yu, Kanglun et al. (2018) Loss of Hdac3 in osteoprogenitors increases bone expression of osteoprotegerin, improving systemic insulin sensitivity. J Cell Physiol 233:2671-2680
Pfister, Katie M; Zhang, Lei; Miller, Neely C et al. (2018) Early body composition changes are associated with neurodevelopmental and metabolic outcomes at 4 years of age in very preterm infants. Pediatr Res 84:713-718
Roelfsema, Ferdinand; Yang, Rebecca J; Veldhuis, Johannes D (2018) Differential Effects of Estradiol and Progesterone on Cardiovascular Risk Factors in Postmenopausal Women. J Endocr Soc 2:794-805
Halper, Alyssa; Sanchez, Belen; Hodges, James S et al. (2018) Bone mineral density and body composition in children with congenital adrenal hyperplasia. Clin Endocrinol (Oxf) 88:813-819
Roelfsema, Ferdinand; Yang, Rebecca J; Takahashi, Paul Y et al. (2018) Effects of Toremifene, a Selective Estrogen Receptor Modulator, on Spontaneous and Stimulated GH Secretion, IGF-I, and IGF-Binding Proteins in Healthy Elderly Subjects. J Endocr Soc 2:154-165
Egbert, Amy Heard; Wilfley, Denise E; Eddy, Kamryn T et al. (2018) Attention-Deficit/Hyperactivity Disorder Symptoms Are Associated with Overeating with and without Loss of Control in Youth with Overweight/Obesity. Child Obes 14:50-57
Qiu, Xiaoxue; Guo, Hong; Yang, Junshu et al. (2018) Down-regulation of guanylate binding protein 1 causes mitochondrial dysfunction and cellular senescence in macrophages. Sci Rep 8:1679
Mason, Tyler B; Smith, Kathryn E; Crosby, Ross D et al. (2018) Does the eating disorder examination questionnaire global subscale adequately predict eating disorder psychopathology in the daily life of obese adults? Eat Weight Disord 23:521-526
Levis, Brooke; Benedetti, Andrea; Riehm, Kira E et al. (2018) Probability of major depression diagnostic classification using semi-structured versus fully structured diagnostic interviews. Br J Psychiatry 212:377-385
Goldschmidt, Andrea B; Crosby, Ross D; Cao, Li et al. (2018) A preliminary study of momentary, naturalistic indicators of binge-eating episodes in adults with obesity. Int J Eat Disord 51:87-91

Showing the most recent 10 out of 717 publications