The Administrative Core is responsible for allocation, management, and oversight of DRC resources. The Administrative Core, in coordination with the DRC Executive Committee and the two Advisory Committees (Internal and External) establishes and implements program objectives and Core utilization targets, reviews and approves membership applications, organizes the research base into coherent interest groups and facilitates communication among them, oversees program enrichment activities, and administers the P&F and enrichment programs. The Core is responsible for allocation of resources among different Cores based on workflows, user base, technical, and strategic considerations. It is also responsible for administrative oversight of personnel actions, financial management and reporting, conforming to University standards for space and resource utilization, and providing appropriate human resource management to Core Directors to implement billing and expedite technical support and personnel actions. The Core is also responsible for development, maintenance, and timely update of the DRC website. The Core ensures continuity of operations in the event of replacement of Core leadership or technical personnel, and oversees compliance with University regulations regarding human subjects, animal experimentation, technology transfer, hazardous and radioactive maternal compliance. The Administrative Core leadership represents the DRC within the faculty of the College of Physician &Surgeons, and is responsible to ensure that the DRC figures prominently in the school's strategic and programmatic goals. Dr. Domenico Accili, MD will serve as Director of the Administrative Core. In this capacity, he will oversee DRC activities, including DRC membership, administration of Core Facilities and P&F program, convene the Advisory Boards and attend ready meetings of the DRC Pis. He will be assisted by Dr. Rudolph Leibel, DRC Co-PI, Director of Core A (Genomics), and Associate Director for Pilot &Feasibility Program. Together, the Co-PIs will integrate DRC activities with institutional Centers and initiatives that can benefit diabetes research and training. They will ensure the seamless operation of DRC Core facilities and their integration with University-wide facilities (including the NY Obesity Research Center) to avoid duplication of costs and effort. In a similar vein, the Co-PIs will proactively integrate DRC activities with those of other DRCs, especially the neighboring Northeast Centers, as well as other NIDDK consortial and program activities, e.g.. Mouse Metabolic Phenotyping Centers and Beta Cell Biology Consortium.
The Administrative Core is essential to develop the strategy of the Columbia DRC and implement its interdependent elements. It provides overall structural and organizational leadership, it ensures the proper oversight of financial and program enrichment tools, including Core Facilities, and it enables appropriate external review and oversight It integrates different elements of the program to ensure more rapid and efficient access of diabetes researchers to needed resources, encouraging collaborations.
|Arnes, Luis; Liu, Zhaoqi; Wang, Jiguang et al. (2018) Comprehensive characterisation of compartment-specific long non-coding RNAs associated with pancreatic ductal adenocarcinoma. Gut :|
|Tamucci, Kirstin A; Namwanje, Maria; Fan, Lihong et al. (2018) The dark side of browning. Protein Cell 9:152-163|
|Accili, Domenico (2018) Insulin Action Research and the Future of Diabetes Treatment: The 2017 Banting Medal for Scientific Achievement Lecture. Diabetes 67:1701-1709|
|Ravussin, Yann; Edwin, Ethan; Gallop, Molly et al. (2018) Evidence for a Non-leptin System that Defends against Weight Gain in Overfeeding. Cell Metab 28:289-299.e5|
|Sui, Lina; Danzl, Nichole; Campbell, Sean R et al. (2018) ?-Cell Replacement in Mice Using Human Type 1 Diabetes Nuclear Transfer Embryonic Stem Cells. Diabetes 67:26-35|
|Laferrère, Blandine; Pattou, François (2018) Weight-Independent Mechanisms of Glucose Control After Roux-en-Y Gastric Bypass. Front Endocrinol (Lausanne) 9:530|
|Shah, Ankit; Levesque, Kiarra; Pierini, Esmeralda et al. (2018) Effect of sitagliptin on glucose control in type 2 diabetes mellitus after Roux-en-Y gastric bypass surgery. Diabetes Obes Metab 20:1018-1023|
|Haeusler, Rebecca A; McGraw, Timothy E; Accili, Domenico (2018) Biochemical and cellular properties of insulin receptor signalling. Nat Rev Mol Cell Biol 19:31-44|
|Kraakman, Michael J; Liu, Qiongming; Postigo-Fernandez, Jorge et al. (2018) PPAR? deacetylation dissociates thiazolidinedione's metabolic benefits from its adverse effects. J Clin Invest 128:2600-2612|
|Kumar, Brahma V; Kratchmarov, Radomir; Miron, Michelle et al. (2018) Functional heterogeneity of human tissue-resident memory T cells based on dye efflux capacities. JCI Insight 3:|
Showing the most recent 10 out of 225 publications