Abstract

The Animal Models and Phenotyping Core will provide support for CNRU and other investigators in two major areas; the provision of new animal models through either transgenic or gene targeting techniques and the phenotypic characterization of animals for behavioral characteristics, body composition or metabolic parameters relevant to the overall goal of the CNRU in investigating the effects of nutritional programming on the development of obesity/diabetes. The Core will provide direct services and/or training for CNRU investigators and other faculty. The Core Director (David York) and Assoc. Director (Randy Mynatt) have long experience in animal physiology working with all the behavioral and metabolic phenotyping methods and the transgenic/gene targeting procedures that are included in this Core. Both user fees and institutional support will fund the Core. The Core staff will also work with faculty to develop additional established procedures or to develop new innovative methods that are relevant to the overall goal of the CNRU and that will enhance the productivity and research quality of the investigators.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK072476-02
Application #
7311650
Study Section
Special Emphasis Panel (ZDK1)
Project Start
Project End
Budget Start
2006-09-01
Budget End
2007-08-31
Support Year
2
Fiscal Year
2006
Total Cost
$229,592
Indirect Cost

  Institution

Name
Lsu Pennington Biomedical Research Center
Department
Type
DUNS #
611012324
City
Baton Rouge
State
LA
Country
United States
Zip Code
70808

  Publications

Yu, Sangho; Münzberg, Heike (2018) Testing Effects of Chronic Chemogenetic Neuronal Stimulation on Energy Balance by Indirect Calorimetry. Bio Protoc 8:
Bruce-Keller, Annadora J; Salbaum, J Michael; Berthoud, Hans-Rudolf (2018) Harnessing Gut Microbes for Mental Health: Getting From Here to There. Biol Psychiatry 83:214-223
Kaviani, Sepideh; Schoeller, Dale A; Ravussin, Eric et al. (2018) Determining the Accuracy and Reliability of Indirect Calorimeters Utilizing the Methanol Combustion Technique. Nutr Clin Pract 33:206-216
Peterson, Courtney M; Beyl, Robbie A; Marlatt, Kara L et al. (2018) Effect of 12 wk of resistant starch supplementation on cardiometabolic risk factors in adults with prediabetes: a randomized controlled trial. Am J Clin Nutr 108:492-501
Elbers, Jean P; Brown, Mary B; Taylor, Sabrina S (2018) Identifying genome-wide immune gene variation underlying infectious disease in wildlife populations - a next generation sequencing approach in the gopher tortoise. BMC Genomics 19:64
Graf, Brittany L; Zhang, Li; Corradini, Maria G et al. (2018) Physicochemical differences between malanga (Xanthosoma sagittifolium) and potato (Solanum tuberosum) tubers are associated with differential effects on the gut microbiome. J Funct Foods 45:268-276
Clark, Richard V; Walker, Ann C; Miller, Ram R et al. (2018) Creatine ( methyl-d3) dilution in urine for estimation of total body skeletal muscle mass: accuracy and variability vs. MRI and DXA. J Appl Physiol (1985) 124:1-9
Most, Jasper; Gilmore, L Anne; Altazan, Abby D et al. (2018) Propensity for adverse pregnancy outcomes in African-American women may be explained by low energy expenditure in early pregnancy. Am J Clin Nutr 107:957-964
White, Ursula A; Fitch, Mark D; Beyl, Robbie A et al. (2018) Racial differences in in vivo adipose lipid kinetics in humans. J Lipid Res 59:1738-1744
Stephens, Jacqueline M; Bailey, Jennifer L; Hang, Hardy et al. (2018) Adipose Tissue Dysfunction Occurs Independently of Obesity in Adipocyte-Specific Oncostatin Receptor Knockout Mice. Obesity (Silver Spring) 26:1439-1447

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