The Administrative Core plays a key role in coordinating the interactions among the broad and diverse elements of the Cystic Fibrosis Research Center (CFRC) of the University of Pittsburgh. Dr. Raymond A. Frizzell is the Core Center Director, and he is assisted by the Associate Director, Dr. Joseph Pilewski. Together, they oversee the Center's scientific and administrative operations. Dr. Frizzell has a long-standing commitment to CF research and an even longer record of continuous NIH support. He will: ? Work closely with the Center Committee to integrate the program and its scientific interactions within the University and with outside collaborators, its interactions with the NIDDK concerning plans and progress reports and information transfer to the lay community, ? Monitor the utilization, effective operation and use priorities of the Research Cores, ? Assure quality control concerning the selection and execution of pilot/feasibility studies, and ? Organize and operate an annual review of these activities by the Center's Internal and External Advisory Committees. Ms. Cindy Pokora (administrative assistant to Dr. Frizzell) will be responsible for coordinating the activities of the Center's interactive components (scheduling seminars, joint lab meetings, journal clubs, bimonthly meetings of the Center Committee, annual meetings of the Internal and External Advisory Committees) and maintain Center website content. She will prepare Progress Reports, facilitate interactions with outside agencies (NIH and CFF) and collaborators, and oversee the production and distribution of regular budget reports from the accounting staff to Core and Pilot PIs.

Public Health Relevance

The Administrative Core is the organizing focus for the CF Research Center and the P30 Core Center. It monitors core use, assures qualitty control of the cores and pilot/feasibility projects, organizes the annual Center review and communicates outcomes to the NIDDK, University and lay communities.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK072506-10
Application #
8685246
Study Section
Special Emphasis Panel (ZDK1)
Project Start
Project End
Budget Start
2014-06-01
Budget End
2015-05-31
Support Year
10
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of Pittsburgh
Department
Type
DUNS #
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Woodcock, Chen-Shan Chen; Huang, Yi; Woodcock, Steven R et al. (2018) Nitro-fatty acid inhibition of triple-negative breast cancer cell viability, migration, invasion, and tumor growth. J Biol Chem 293:1120-1137
Sannino, Sara; Guerriero, Christopher J; Sabnis, Amit J et al. (2018) Compensatory increases of select proteostasis networks after Hsp70 inhibition in cancer cells. J Cell Sci 131:
McAleer, Jeremy P; Kolls, Jay K (2018) Contributions of the intestinal microbiome in lung immunity. Eur J Immunol 48:39-49
Dar, Haider H; Tyurina, Yulia Y; Mikulska-Ruminska, Karolina et al. (2018) Pseudomonas aeruginosa utilizes host polyunsaturated phosphatidylethanolamines to trigger theft-ferroptosis in bronchial epithelium. J Clin Invest 128:4639-4653
Pradhan-Sundd, Tirthadipa; Vats, Ravi; Russell, Jacquelyn O et al. (2018) Dysregulated Bile Transporters and Impaired Tight Junctions During Chronic Liver Injury in Mice. Gastroenterology 155:1218-1232.e24
Hvorecny, Kelli L; Dolben, Emily; Moreau-Marquis, Sophie et al. (2018) An epoxide hydrolase secreted by Pseudomonas aeruginosa decreases mucociliary transport and hinders bacterial clearance from the lung. Am J Physiol Lung Cell Mol Physiol 314:L150-L156
Saydmohammed, Manush; Yagi, Hisato; Calderon, Michael et al. (2018) Vertebrate myosin 1d regulates left-right organizer morphogenesis and laterality. Nat Commun 9:3381
Caves, Elizabeth A; Cook, Sarah A; Lee, Nara et al. (2018) Air-Liquid Interface Method To Study Epstein-Barr Virus Pathogenesis in Nasopharyngeal Epithelial Cells. mSphere 3:
Perkins, Lydia A; Fisher, Gregory W; Naganbabu, Matharishwan et al. (2018) High-Content Surface and Total Expression siRNA Kinase Library Screen with VX-809 Treatment Reveals Kinase Targets that Enhance F508del-CFTR Rescue. Mol Pharm 15:759-767
Qu, Yanyan; Olonisakin, Tolani; Bain, William et al. (2018) Thrombospondin-1 protects against pathogen-induced lung injury by limiting extracellular matrix proteolysis. JCI Insight 3:

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