This proposal seeks continued funding for the JHU-UMD Diabetes Research Center (DRC). The proposed Center will continue to involve investigators from Johns Hopkins University and the University of Maryland. These investigators have primary appointments in numerous departments within and between these Institutions;and while their scientific backgrounds are diverse, they share a common interest in diabetes and endocrinology research and many have established collaborations.
The aims of the Center are the following: 1) to foster collaborative, multidisciplinary diabetes and endocrinology research in a supportive environment;2) to enhance the clinical and basic research capabilities of established diabetes investigators;3) to encourage investigators not involved in diabetes research to become interested in pursuing problems related to diabetes and endocrinology;4) to develop, implement and evaluate programs that deliver cost effective health care for the treatment of persons with diabetes;5) to speed the translation of advances in basic biomedical and genetic research to the clinical arena where they may be applied to the diagnosis and treatment of persons with diabetes;and 6) to inform others in both professional and lay settings of the accomplishments, opportunities and advancements in diabetes research and training. This application contains six separate components: Administrative, Biomedical Research, Pilot and Feasibility, Enrichment, a Regional Shared Resource core, and a Shared Research Core and expansion of the P&F program to a Historically Black University, Howard University College of Medicine. The Administrative Component will be responsible for overseeing the operation of the Center as a whole. The Biomedical Research Component will consist of five Core Laboratories to foster collaborative diabetes research. A Pilot and Feasibility Component will foster the participation and interaction of junior investigators with established investigators in research'related to diabetes. The Enrichment Program will facilitate the interaction within and between Johns Hopkins University and the University of Maryland.

Public Health Relevance

The JHU-UMD Diabetes Research Center strives to understand the causes of both type 1 and 2 diabetes and promote translational research that is aimed at reducing the burden of these diseases in the U.S. This center has a unique focus on childhood diabetes and diabetes that affects minority populations.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK079637-07
Application #
8629726
Study Section
Special Emphasis Panel (ZDK1-GRB-S (O2))
Program Officer
Hyde, James F
Project Start
2008-02-01
Project End
2018-01-31
Budget Start
2014-02-01
Budget End
2015-01-31
Support Year
7
Fiscal Year
2014
Total Cost
$1,942,750
Indirect Cost
$499,100
Name
Johns Hopkins University
Department
Pediatrics
Type
Schools of Medicine
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Fesseha, Betiel K; Abularrage, Christopher J; Hines, Kathryn F et al. (2018) Association of Hemoglobin A1c and Wound Healing in Diabetic Foot Ulcers. Diabetes Care 41:1478-1485
Bilal, Usama; Hill-Briggs, Felicia; Sánchez-Perruca, Luis et al. (2018) Association of neighbourhood socioeconomic status and diabetes burden using electronic health records in Madrid (Spain): the HeartHealthyHoods study. BMJ Open 8:e021143
Kushwaha, Priyanka; Wolfgang, Michael J; Riddle, Ryan C (2018) Fatty acid metabolism by the osteoblast. Bone 115:8-14
Riddle, Ryan C; Clemens, Thomas L (2017) Bone Cell Bioenergetics and Skeletal Energy Homeostasis. Physiol Rev 97:667-698
Saloustros, Emmanouil; Salpea, Paraskevi; Starost, Matthew et al. (2017) Prkar1a gene knockout in the pancreas leads to neuroendocrine tumorigenesis. Endocr Relat Cancer 24:31-40
Hassoon, Ahmed; Bydon, Mohamad; Kerezoudis, Panagiotis et al. (2017) Chronic low-back pain in adult with diabetes: NHANES 2009-2010. J Diabetes Complications 31:38-42
Kim, Soohyun P; Li, Zhu; Zoch, Meredith L et al. (2017) Fatty acid oxidation by the osteoblast is required for normal bone acquisition in a sex- and diet-dependent manner. JCI Insight 2:
Gu, Cihang; Warkentin, Sarah; Mais, Laís Amaral et al. (2017) Ethnic differences in parental feeding behaviors in UK parents of preschoolers. Appetite 113:398-404
Vakil, Rachit M; Chaudhry, Zoobia W; Doshi, Ruchi S et al. (2017) Commercial Programs' Online Weight-Loss Claims Compared to Results from Randomized Controlled Trials. Obesity (Silver Spring) 25:1885-1893
Tseng, Eva; Yeh, Hsin-Chieh; Maruthur, Nisa M (2017) Metformin Use in Prediabetes Among U.S. Adults, 2005-2012. Diabetes Care 40:887-893

Showing the most recent 10 out of 755 publications