The Hopkins Digestive Diseases Basic and Translational Research Core Center Administrative Core is the glue which forms the structure of this Center by carrying out communications among the Center and Research Base investigators and Core Directors, performing budget management, serving as a repertoire for the software used by Center investigators and organizing all Center activities. In this way the Research Base of 50 investigataors (38 full members 12 associate members) are allowed to efficiently interact with the components ofthe Core Center, including the a) Administrative Core;b) 4 Scientific Cores-3 basic science [1) Proteomics;2) Imaging;3) Mouse Physiology] and a Translational Research Enhancement Core;c) Pilot Project Program;d) Enrichement Program which has multiple components. The specific functions ofthe Administrative Core include: a) Provide administrative and financial management ofthe Core Center;b) Provide monthly financial statements to Core Directors;c) Monitor use and perform charge-back for each Core 6x year;d) Inform Research Base weekly of work-in-progress meeting topic, lectures of interest around Hopkins, NIH funding opportunities, GI histology findings on mouse models studied by Research Base, Visiting Professor Program, Yearly Scientic Symposium, Yearly Retreat;e) Arrange a yearly meeting of External Scientific Advisory Committee, every other month meeting of Internal Executive Committee and Focus Groups, 6x year Visiting Professor Program, and yearly working group meetings for each Core;f) Organize and run yearly Research Base one day retreat;g) Organize and run yearly 1-2 day long Research Symposium;h) Organize and publish yearly Core Center newsletter;i) Assist in preparation of yearly DDBTRCC Progress Report for NIH;j) Prepare notes from yearly External Scientific Advisory Committee meeting;k) Organize and administer Pilot Project Program;1) Organize and administer Mini-Sabbatical Program;m) Help Research Base comply with JHUSOM, NIH, other governmental guidelines relating to research;n) Develop web page for Imaging and Mouse Physiology Cores;o) Help manage DDBTRCC service contracts;p) Help negotiate Core Center purchasing of equipment, service contracts, software; q) Serve as a repository for licenses for software purchased for Research Base and Core use.

Public Health Relevance

The Administrafive core is the glue which forms the structure of this Core Center by communicating Core Center activities to the Research Base investigators. Core Directors, and Core Center leadership, performing budget management and serving as the site of storage of the Core Center software that is made available to the Research Base.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK089502-03
Application #
8461239
Study Section
Special Emphasis Panel (ZDK1-GRB-8)
Project Start
Project End
Budget Start
2013-06-01
Budget End
2014-05-31
Support Year
3
Fiscal Year
2013
Total Cost
$398,243
Indirect Cost
$147,478
Name
Johns Hopkins University
Department
Type
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Liu, Xi; Abraham, John M; Cheng, Yulan et al. (2018) Synthetic Circular RNA Functions as a miR-21 Sponge to Suppress Gastric Carcinoma Cell Proliferation. Mol Ther Nucleic Acids 13:312-321
Liu, Xi; Cheng, Yulan; Abraham, John M et al. (2018) Modeling Wnt signaling by CRISPR-Cas9 genome editing recapitulates neoplasia in human Barrett epithelial organoids. Cancer Lett 436:109-118
Dejea, Christine M; Fathi, Payam; Craig, John M et al. (2018) Patients with familial adenomatous polyposis harbor colonic biofilms containing tumorigenic bacteria. Science 359:592-597
Aberle, M R; Burkhart, R A; Tiriac, H et al. (2018) Patient-derived organoid models help define personalized management of gastrointestinal cancer. Br J Surg 105:e48-e60
Singh, Varsha; Yang, Jianbo; Yin, Jianyi et al. (2018) Cholera toxin inhibits SNX27-retromer-mediated delivery of cargo proteins to the plasma membrane. J Cell Sci 131:
Chung, Liam; Thiele Orberg, Erik; Geis, Abby L et al. (2018) Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells. Cell Host Microbe 23:203-214.e5
Liu, Liansheng; Zhu, Yaohui; Noë, Michaël et al. (2018) Neuronal Transforming Growth Factor beta Signaling via SMAD3 Contributes to Pain in Animal Models of Chronic Pancreatitis. Gastroenterology 154:2252-2265.e2
Nakamura, Hideki; Lee, Albert A; Afshar, Ali Sobhi et al. (2018) Intracellular production of hydrogels and synthetic RNA granules by multivalent molecular interactions. Nat Mater 17:79-89
Becker, Laren; Nguyen, Linh; Gill, Jaspreet et al. (2018) Age-dependent shift in macrophage polarisation causes inflammation-mediated degeneration of enteric nervous system. Gut 67:827-836
Pierson, Hannah; Muchenditsi, Abigael; Kim, Byung-Eun et al. (2018) The Function of ATPase Copper Transporter ATP7B in Intestine. Gastroenterology 154:168-180.e5

Showing the most recent 10 out of 232 publications